t(15;17)

A cytogenetic abnormality that involves a translocation between chromosomes 15 and 17.
National Institutes of Health

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Highly Cited
2010
Highly Cited
2010
Diagnostic karyotype provides the framework for risk-stratification schemes in acute myeloid leukemia (AML); however, the… (More)
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Highly Cited
2006
Highly Cited
2006
Tightly regulated expression of the transcription factor PU.1 is crucial for normal hematopoiesis. PU.1 knockdown mice develop… (More)
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Highly Cited
2004
Highly Cited
2004
BACKGROUND In patients with acute myeloid leukemia (AML) a combination of methods must be used to classify the disease, make… (More)
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Highly Cited
2002
Highly Cited
2002
Constitutive activation of the FLT3 receptor tyrosine kinase, either by internal tandem duplication (ITD) of the juxtamembrane… (More)
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Highly Cited
2002
Highly Cited
2002
FLT3 length mutation (FLT3-LM) is a molecular marker potentially useful for the characterization of acute myeloid leukemia (AML… (More)
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Review
1999
Review
1999
Prospective studies on the detection of minimal residual disease (MRD) in acute leukemia patients have shown that large-scale MRD… (More)
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Highly Cited
1998
Highly Cited
1998
Cytogenetics is considered one of the most valuable prognostic determinants in acute myeloid leukemia (AML). However, many… (More)
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Highly Cited
1991
Highly Cited
1991
Acute promyelocytic leukemia (APL) is a well-defined entity among acute leukemia, cytogenetically characterized by a t(15;17… (More)
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Highly Cited
1991
Highly Cited
1991
A unique mRNA produced in leukemic cells from a t(15;17) acute promyelocytic leukemia (APL) patient encodes a fusion protein… (More)
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Highly Cited
1990
Highly Cited
1990
RETINOIC acid is a vitamin A derivative with striking effects on development and cell differentiation1–3. Several nuclear… (More)
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