systemic therapy

Treatment using substances that travel through the bloodstream, reaching and affecting cells all over the body.

Topic mentions per year

Topic mentions per year

1946-2017
050019462016

Papers overview

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Review
2014
Review
2014
INTRODUCTION Human epidermal growth factor receptor (HER) 2 is overexpressed in 20 - 25% of breast cancers, and has historically… (More)
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Highly Cited
2011
Highly Cited
2011
CONTEXT Sentinel lymph node dissection (SLND) accurately identifies nodal metastasis of early breast cancer, but it is not clear… (More)
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Highly Cited
2009
Highly Cited
2009
UNLABELLED PURPOSE To improve on current standards for breast cancer prognosis and prediction of chemotherapy benefit by… (More)
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Highly Cited
2009
Highly Cited
2009
BACKGROUND Gene expression profiling of breast cancer has identified two biologically distinct estrogen receptor (ER)-positive… (More)
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Highly Cited
2009
Highly Cited
2009
BACKGROUND Most cases of hepatocellular carcinoma occur in the Asia-Pacific region, where chronic hepatitis B infection is an… (More)
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Highly Cited
2008
Highly Cited
2008
BACKGROUND No effective systemic therapy exists for patients with advanced hepatocellular carcinoma. A preliminary study… (More)
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Highly Cited
2005
Highly Cited
2005
BACKGROUND Interest in the use of preoperative systemic treatment in the management of breast cancer has increased because such… (More)
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Highly Cited
2002
Highly Cited
2002
BACKGROUND A more accurate means of prognostication in breast cancer will improve the selection of patients for adjuvant systemic… (More)
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Highly Cited
2002
Highly Cited
2002
PURPOSE To define outcome data and prognostic criteria for patients with metastatic renal cell carcinoma (RCC) treated with… (More)
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Highly Cited
2000
Highly Cited
2000
PURPOSE To examine the relationship between pathologic margin status and outcome at 8 years after breast-conserving surgery and… (More)
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