Skip to search formSkip to main contentSkip to account menu
You are currently offline. Some features of the site may not work correctly.

symphytine

Known as: 2-Butenoic acid, 2-methyl-, 7-((2,3-dihydroxy-2-(1-methylethyl)-1-oxobutoxy)methyl)-2,3,5,7a-tetrahydro-1H-pyrrolizin-1-yl ester, (1R-(1alpha(E),7(2S*,3S*),7abeta))- 
National Institutes of Health

Related topics

Related topics

1 relation

Broader (1)

Pyrrolizidine Alkaloids

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2010
Review
2010
Metabolism, Genotoxicity, annd Carcinogenicity of Comfrey
Comfrey has been consumed by humans as a vegetable and a tea and used as an herbal medicine for more than 2000 years. Comfrey… Expand
2006
2006
Chemotaxonomical investigations of theSymphytum officinale polyploid complex andS. asperum (Boraginaceae): The pyrrolizidine alkaloids
By means of thin layer chromatography in conjunction with mass spectrometry the pyrrolizidine alkaloid patterns derived… Expand
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
2005
2005
Pyrrolizidine alkaloids fromSymphytum officinale L. and their percutaneous absorption in rats
An analysis of a commercial sample of Symphyti radix originating from Poland with a total alkaloid content of 0.07% revealed the… Expand
  • figure 1
  • table 1
2004
2004
Analysis of herbal teas made from the leaves of comfrey (Symphytum officinale): reduction of N-oxides results in order of magnitude increases in the measurable concentration of pyrrolizidine…
Abstract Objectives: To determine the relative quantities of two hepatotoxic pyrrolizidine alkaloids, symphytine and echimidine… Expand
2004
2004
Chemotaxonomy of theSymphytum officinale agg. (Boraginaceae)
In a chemotaxonomic study of the genusSymphytum pyrrolizidine alkaloids and triterpenes were used as chemotaxonomical markers. A… Expand
  • figure 1
  • figure 2
  • table 1
  • table 2
  • figure 4
2004
2004
Chemo- and karyotaxonomic studies on some rhizomatous species of the genusSymphytum (Boraginaceae)
InS. tuberosum subspp.tuberosum andnodosum, S. grandiflorum andS. ibericum the presence of the pyrrolizidine alkaloids… Expand
  • figure 2
  • figure 3
2001
2001
Isolation of symlandine from the roots of common comfrey (Symphytum officinale) using countercurrent chromatography.
Three pyrrolizidine alkaloids, symlandine, symphytine, and echimidine (1-3), were isolated from the roots of Symphytum officinale… Expand
Review
2000
Review
2000
The efficacy and safety of comfrey
Abstract Herbal medication has gathered increasing recognition in recent years with regard to both treatment options and health… Expand
Highly Cited
1979
Highly Cited
1979
Induction of hepatic tumors in rats by senkirkine and symphytine.
The carcinogenicity of the pyrrolizidine alkaloids senkirkine and symphytine was studied in male inbred ACI rats. Animals were… Expand
1968
1968
Studies on constituents of crude drugs. I. Alkaloids of Symphytum officinale Linn.
Two pyrrolizidine alkaloids, symphytine (I), a new compound, and echimidine (II) have been isolated from the dried roots of… Expand
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy, Terms of Service, and Dataset License
ACCEPT & CONTINUE