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suriclone

Known as: 6-(7-chloro-1,8-naphthyridin-2-yl)-2,3,6,7-tetrahydro-7-oxo-5H-(1,4)dithiino(2,3-c)pyrrol-5-yl-4-methylpiperazine-1-carboxylate, (8-(7-chloro(1,8)naphthyridin-2-yl)-7-oxo-2,5-dithia-8-azabicyclo(4.3.0)non-10-en-9-yl) 4-methylpiperazine-1-carboxylate, (R,S)-6-(7-Chlor-1,8-naphthyridin-2-yl)-3,5,6,7-tetrahydro-5-oxo-2H-(1,4)dithixino(2,3-c)pyrrol-7-yl-4-methyl-1-piperazinylcarboxylat 
 
National Institutes of Health

Papers overview

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2005
2005
The anxiolytic activity and tolerance of four doses of suriclone (0.1, 0.2, 0.3 and 0.4 mg tid), diazepam (5 mg tid), and placebo… Expand
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2004
2004
Twelve healthy subjects received single oral doses of 0.4 mg suriclone (SU), 7.5 mg zopiclone (ZO) and placebo, alone and… Expand
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Highly Cited
1995
Highly Cited
1995
Effects of benzodiazepine (diazepam, lorazepam) and benzodiazepine-like anxiolytics (alpidem, suriclone) and a 5-HT-3 antagonist… Expand
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1993
1993
A high-performance liquid chromatographic assay with diode-array detection has been developed for the toxicological screening of… Expand
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Highly Cited
1986
Highly Cited
1986
The effects of a variety of minor tranquilizers and of benzodiazepine inverse agonists on the stress-induced increase in frontal… Expand
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Highly Cited
1985
Highly Cited
1985
Among the non-benzodiazepine compounds which have been found to interact with the "GABA receptor-BZ receptor-chloride channel… Expand
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Highly Cited
1985
Highly Cited
1985
Social interaction (SI) between two unfamiliar male rats in a dimly lit, familiar environment has been investigated as a model of… Expand
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1985
1985
Rat hippocampus membranes were treated with several protein modifying reagents (iodoacetamide, N-ethylmaleimide… Expand
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Highly Cited
1984
Highly Cited
1984
The interactions of zopiclone and suriclone, representatives of nonbenzodiazepine cyclopyrrolone anxiolytics, with central-type… Expand
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Highly Cited
1983
Highly Cited
1983
Abstract: Suriclone (RP 31,264), like zopiclone (RP 27, 267), belongs to the family of cyclopyrrolones and is chemically entirely… Expand
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