suppression by virus of host RIG-I signaling pathway

Known as: inhibition by virus of host RIG-I signaling, suppression by virus of host DDX58 signaling pathway, suppression by virus of host RIG-I signalling pathway 
Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of the series of molecular signals generated as a consequence… (More)
National Institutes of Health

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Highly Cited
2013
Highly Cited
2013
RIG-I is a critical RNA virus sensor that serves to initiate antiviral innate immunity. However, posttranslational regulation of… (More)
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Highly Cited
2011
Highly Cited
2011
RIG-I is a cytosolic pathogen recognition receptor that engages viral RNA in infected cells to trigger innate immune defenses… (More)
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Highly Cited
2011
Highly Cited
2011
RIG-I is a key innate immune pattern-recognition receptor that triggers interferon expression upon detection of intracellular 5… (More)
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Highly Cited
2010
Highly Cited
2010
RNA virus infection is recognized by the RIG-I-like receptors RIG-I and MDA5, which induce antiviral responses including the… (More)
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Highly Cited
2010
Highly Cited
2010
RIG-I detects invading viral RNA and activates the transcription factors NF-kappaB and IRF3 through the mitochondrial protein… (More)
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Highly Cited
2010
Highly Cited
2010
Recognition of invading viruses by the host is elicited by cellular sensors which trigger signaling cascades that lead to type I… (More)
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Highly Cited
2008
Highly Cited
2008
Alpha/beta interferon immune defenses are essential for resistance to viruses and can be triggered through the actions of the… (More)
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Highly Cited
2008
Highly Cited
2008
Innate immune defences are essential for the control of virus infection and are triggered through host recognition of viral… (More)
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Highly Cited
2008
Highly Cited
2008
Innate immunity is critically dependent on the rapid production of interferon in response to intruding viruses. The intracellular… (More)
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Highly Cited
2007
Highly Cited
2007
Retinoic acid-inducible gene I (RIG-I) plays a pivotal role in the regulation of cytokine production induced by pathogens. The… (More)
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