superoxide dismutase 1

Known as: Superoxide Dismutase, Cu-Zn, Superoxide Dismutase-1 [Chemical/Ingredient], Cu-Zn Superoxide Dismutase 
A superoxide dismutase (SOD1) that requires copper and zinc ions for its activity to destroy SUPEROXIDE FREE RADICALS within the CYTOPLASM. Mutations… (More)
National Institutes of Health

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Highly Cited
2011
Highly Cited
2011
Deposition of proteins of aberrant conformation is the hallmark of many neurodegenerative diseases. Misfolding of the normally… (More)
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Highly Cited
2011
Highly Cited
2011
Human wild-type superoxide dismutase-1 (wtSOD1) is known to coaggregate with mutant SOD1 in familial amyotrophic lateral… (More)
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Highly Cited
2006
Highly Cited
2006
Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease afflicting the voluntary motor system. More than 100 different… (More)
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Highly Cited
2006
Highly Cited
2006
Mutation in superoxide dismutase-1 (SOD1), which is a cause of ALS, alters the folding patterns of this protein. Accumulation of… (More)
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Highly Cited
2005
Highly Cited
2005
An increasing body of evidence suggests that mitochondrial dysfunction plays an important role in the pathogenesis of familial… (More)
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Highly Cited
2004
Highly Cited
2004
Effects of water stress on superoxide dismutase (SOD) activities, changes in protein content, leaf water potential (Ψ l ) and… (More)
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Highly Cited
2004
Highly Cited
2004
Mutant forms of superoxide dismutase-1 (SOD1) cause amyotrophic lateral sclerosis (ALS) by an unknown noxious mechanism. Using an… (More)
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Highly Cited
2003
Highly Cited
2003
BACKGROUND Chronic renal failure (CRF) is associated with oxidative stress, the mechanism of which remains uncertain. Superoxide… (More)
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Highly Cited
1994
Highly Cited
1994
Familial amyotrophic lateral sclerosis (FALS) has been linked to mutations in the homodimeric enzyme Cu/Zn superoxide dismutase 1… (More)
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Highly Cited
1993
Highly Cited
1993
NEURONAL injury resulting from acute brain insults and some neurodegenerative diseases implicates N-methyl-D-aspartate (NMDA… (More)
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