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sulofenur

Known as: 1H-Indene-5-sulfonamide, N-(((4-chlorophenyl)amino)carbonyl)-2,3-dihydro-, ISCU, N-(5-indanylsulfonyl)-N'-(4-chlorophenyl)urea 
A diarylsulfonylurea with potential antineoplastic activity. Sulofenur's antineoplastic mechanism of action is unknown. (NCI04)
National Institutes of Health

Papers overview

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Highly Cited
2011
Highly Cited
2011
We report on ten individuals with a fatal infantile encephalopathy and/or pulmonary hypertension, leading to death before the age… Expand
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Highly Cited
2011
Highly Cited
2011
BACKGROUND Frataxin, the mitochondrial protein deficient in Friedreich ataxia, a rare autosomal recessive neurodegenerative… Expand
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Highly Cited
2010
Highly Cited
2010
The mechanisms of compromised mitochondrial function under various pathological conditions, including hypoxia, remain largely… Expand
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Highly Cited
2010
Highly Cited
2010
Background Hypoxia in cancers results in the upregulation of hypoxia inducible factor 1 (HIF-1) and a microRNA, hsa-miR-210 (miR… Expand
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Highly Cited
2008
Highly Cited
2008
A myopathy with severe exercise intolerance and myoglobinuria has been described in patients from northern Sweden, with… Expand
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Highly Cited
2006
Highly Cited
2006
Iron-sulfur (Fe-S) clusters are required for the functions of mitochondrial aconitase, mammalian iron regulatory protein 1, and… Expand
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Highly Cited
2006
Highly Cited
2006
A system for the controlled expression of genes in Azotobacter vinelandii by using genomic fusions to the sucrose catabolic… Expand
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Highly Cited
2003
Highly Cited
2003
Iron–sulfur (Fe–S) clusters serve as cofactors in many proteins that have important redox, catalytic, and regulatory functions… Expand
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Highly Cited
2001
Highly Cited
2001
The cysteine desulfurase enzymes NifS and IscS provide sulfur for the biosynthesis of Fe/S proteins. NifU and IscU have been… Expand
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Highly Cited
2000
Highly Cited
2000
Iron-sulfur cluster biosynthesis in both prokaryotic and eukaryotic cells is known to be mediated by two highly conserved… Expand
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