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sulindac sulfone

Known as: (Z)-5-Fluoro-2-methyl-1-[[4-(methylsulfonyl)phenyl]methylene]-1H-indene-3-acetic Acid, Exisulind 
An inactive metabolite of the nonsteroidal, anti-inflammatory agent sulindac. After oral administration, sulindac undergoes extensive… 
National Institutes of Health

Papers overview

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2006
2006
Objectives:In this phase II study, the combination of docetaxel and exisulind (a GMP phosphodiesterase inhibitor) was given to… 
2005
2005
To determine the safety and efficacy, in a dose‐escalation study, of exisulind (an oral sulphone metabolite of sulindac thought… 
2005
2005
Abstract: Sulindac sulfone (FGN‐1, Aptosyn), a metabolite of the nonsteroidal anti‐inflammatory drug sulindac, lacks… 
2004
2004
Angiogenesis, the process of new blood vessel formation, is the key event in the mechanism of several pathological processes… 
Highly Cited
2000
Highly Cited
2000
This is the first report enumerating a superb antiproliferative effect of both sulindac and exisulind on hepatocellular cancer… 
Review
1994
Review
1994
At the National Cancer Institute, Division of Cancer Prevention and Control, the Chemoprevention Branch and Agent Development…