sulindac sulfone

Known as: (Z)-5-Fluoro-2-methyl-1-[[4-(methylsulfonyl)phenyl]methylene]-1H-indene-3-acetic Acid, Exisulind 
An inactive metabolite of the nonsteroidal, anti-inflammatory agent sulindac. After oral administration, sulindac undergoes extensive… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1982-2017
051019822017

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2003
2003
Sulindac, a non-steroidal anti-inflammatory prodrug, is metabolized into pharmacologically active sulfide and sulfone derivatives… (More)
Is this relevant?
Highly Cited
1999
Highly Cited
1999
Sulindac is a non-steroidal anti-inflammatory agent that is related both structurally and pharmacologically to indomethacin. In… (More)
Is this relevant?
Highly Cited
1999
Highly Cited
1999
We examined the activity of two metabolites of sulindac (a nonsteroidal anti-inflammatory drug), sulindac sulfide and sulindac… (More)
Is this relevant?
1999
1999
Sulindac sulfone (Exisulind), a metabolite of the non-steroidal anti-inflammatory drug, sulindac, was evalauted for its effects… (More)
Is this relevant?
1999
1999
OBJECTIVES Recent studies have shown that Exisulind, a sulfone metabolite of the nonsteroidal anti-inflammatory drug (NSAID… (More)
Is this relevant?
1999
1999
Epidemiological and model studies with laboratory animals have provided evidence that nonsteroidal anti-inflammatory drugs reduce… (More)
  • figure 1
  • figure 2
  • table 1
  • table 2
  • table 3
Is this relevant?
1999
1999
Sulindac sulfide, a metabolite of the nonsteroidal antiinflammatory drug (NSAID) sulindac sulfoxide, is effective at reducing… (More)
  • figure 2
  • figure 1
  • figure 5
  • figure 6
Is this relevant?
1998
1998
The sulfone derivative of the non-steroidal anti-inflammatory drug (NSAID), sulindac, has been reported to inhibit mammary and… (More)
Is this relevant?
Highly Cited
1997
Highly Cited
1997
Nonsteroidal anti-inflammatory drugs (NSAIDs), such as sulindac, have cancer chemopreventive properties by a mechanism that has… (More)
  • figure I
  • figure 2
  • table 1
  • table 2
  • table 3
Is this relevant?
Highly Cited
1997
Highly Cited
1997
Sulindac sulfoxide, a commonly prescribed anti-inflammatory drug, has cancer chemopreventive activity. During its metabolism, the… (More)
Is this relevant?