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sulfonyl-pyridazinone inhibitor

 
National Institutes of Health

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Broader (2)

PyridazinesSulfones

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
A new series of pyridazinone derivatives as cholinesterases inhibitors: Synthesis, in vitro activity and molecular modeling studies.
BACKGROUND The pyridazinone nucleus has been incorporated into a wide variety of therapeutically interesting molecules to… Expand
2018
2018
A new compound of thiophenylated pyridazinone IMB5043 showing potent antitumor efficacy through ATM-Chk2 pathway
Through cell-based screening models, we have identified a new compound IMB5043, a thiophenylated pyridazinone, which exerted… Expand
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2018
2018
Diverse chemical and biological potentials of various pyridazine and pyridazinone derivatives
ISSN: 2410-9649 Asif et al / Chemistry International 5(3) (2019) 206-231 iscientic.org. 
2017
2017
Lewis base-catalyzed diastereoselective [3 + 2] cycloaddition reaction of nitrones with electron-deficient alkenes: an access to isoxazolidine derivatives
A Lewis base-catalyzed [3 + 2] cycloaddition reaction of nitrones with electron-deficient alkenes has been achieved under mild… Expand
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Review
2017
Review
2017
Correspondence: Compound 17b and formyl peptide receptor biased agonism in relation to cardioprotective effects in ischaemia-reperfusion injury
In a recent publication1 Qin and co-workers report the biological evaluation of compound 17b2, also referred as (±)−5a3, a chiral… Expand
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Review
2014
Review
2014
Arylazoazines and arylazoazoles as interesting disperse dyes: Recent developments with emphasis on our contribution laboratory outcomes
In this review, we report a survey on the synthesis and application of arylazoazines and arylazoazoles as versatile disperse dyes… Expand
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2013
2013
Composé pyridazinone et utilisation associée
La presente invention concerne un compose pyridazinone de formule (I) et son utilisation comme activateur de resistance induite… Expand
Review
2002
Review
2002
Arylpiperazines with affinity toward alpha(1)-adrenergic receptors.
In the last years, alpha(1) adrenoceptors (alpha(1)-AR) have been the subject of intense research, in part because receptor… Expand
Highly Cited
2001
Highly Cited
2001
Synthesis, biological evaluation, and pharmacophore generation of new pyridazinone derivatives with affinity toward alpha(1)- and alpha(2)-adrenoceptors.
A series of new pyridazin-3(2H)-one derivatives (3 and 4) were evaluated for their in vitro affinity toward both alpha(1)- and… Expand
1986
1986
UDCG 115 a benzimidazo-pyridazinone compound with cardiovascular activity inhibits platelet thrombus formation
 
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