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sulfamethoxazole hydroxylamine

Known as: SMX-HA, sulphamethoxazole hydroxylamine 
 
National Institutes of Health

Papers overview

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2005
2005
Hypersensitivity adverse drug reactions are much more common among patients with acquired immunodeficiency syndrome (AIDS) than… Expand
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2004
2004
Sulphonamide idiosyncratic toxicosis has been reported in 28 dogs. Non-septic polyarthritis and fever occurring after 8 to 21… Expand
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2002
2002
Abstract.Objective: To determine whether the antiprotozoal drug atovaquone inhibits the cytochrome P450 (CYP)2C9-mediated… Expand
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Highly Cited
2001
Highly Cited
2001
Sulphamethoxazole has been associated with the occurrence of hypersensitivity reactions. There is controversy as to whether the… Expand
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Highly Cited
2000
Highly Cited
2000
Cutaneous reactions are the most common manifestation of delayed-type hypersensitivity caused by sulfamethoxazole and dapsone. In… Expand
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2000
2000
1. Reduction of hydroxylamine drug metabolites by NADH-dependent hydroxylamine reductase (NDHR) has been suggested to be involved… Expand
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1999
1999
Sulphamethoxazole undergoes CYP2C9-mediated bioactivation to a hydroxylamine. In this study, we investigated the effect of the… Expand
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1996
1996
Sulfamethoxazole toxicity is putatively initiated by the formation of a hydroxylamine metabolite by cytochromes P450. If this… Expand
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1996
1996
1. Cytochrome P450-mediated bioactivation of sulphamethoxazole to a hydroxylamine has been implicated in the hypersensitivity… Expand
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1994
1994
The formation and elimination of sulphamethoxazole hydroxylamine in relation to the pharmacokinetics of the parent compound and… Expand
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