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succinyldisalicylic acid

Known as: bis(o-carboxyphenyl)succinate, diaspirin 
National Institutes of Health

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2 relations

Broader (1)

Aspirin
analogs & derivatives

Papers overview

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Highly Cited
2005
Highly Cited
2005
General synthesis of thiophene and selenophene-based heteroacenes.
[reaction: see text] A new intramolecular triple cyclization of bis(o-haloaryl)diacetylenes, via dilithiation followed by… 
Review
2005
Review
2005
Artificial O2 carriers: status in 2005.
Donor blood is a limited resource and its transfusion is associated with significant adverse effects. Therefore, alternatives… 
Highly Cited
2000
Highly Cited
2000
Randomized Trial of Diaspirin Cross-linked Hemoglobin Solution as an Alternative to Blood Transfusion after Cardiac Surgery
Background: Risks associated with transfusion of allogeneic blood have prompted development of methods to avoid orreduce blood… 
Highly Cited
1999
Highly Cited
1999
Diaspirin cross-linked hemoglobin (DCLHb) in the treatment of severe traumatic hemorrhagic shock: a randomized controlled efficacy trial.
CONTEXT Severe, uncompensated, traumatic hemorrhagic shock causes significant morbidity and mortality, but resuscitation with an… 
Highly Cited
1999
Highly Cited
1999
Controlled safety study of a hemoglobin-based oxygen carrier, DCLHb, in acute ischemic stroke.
BACKGROUND AND PURPOSE Diaspirin cross-linked hemoglobin (DCLHb) is a purified, cell-free human hemoglobin solution. In animal… 
Highly Cited
1996
Highly Cited
1996
Phase I study of the safety and pharmacologic effects of diaspirin cross-linked hemoglobin solution.
OBJECTIVE To evaluate the safety, pharmacokinetics, and pharmacodynamics of diaspirin cross-linked hemoglobin solution (DCLHb) in… 
Highly Cited
1996
Highly Cited
1996
Role of endothelin in the cardiovascular effects of diaspirin crosslinked and stroma reduced hemoglobin.
OBJECTIVES Diaspirin crosslinked hemoglobin is a resuscitative solution with excellent oxygen-carrying capacity. Diaspirin… 
Highly Cited
1995
Highly Cited
1995
Role of NO mechanism in cardiovascular effects of diaspirin cross-linked hemoglobin in anesthetized rats.
The role of nitric oxide (NO) in the cardiovascular actions of diaspirin cross-linked hemoglobin (DCLHb) was studied in… 
Highly Cited
1993
Highly Cited
1993
A role for endothelin and nitric oxide in the pressor response to diaspirin cross-linked hemoglobin.
Diaspirin-cross-linked hemoglobin (DCLHb; Baxter Healthcare Corp) has potential for clinical use as a hemoglobin-based oxygen… 
Highly Cited
1993
Highly Cited
1993
Use of base deficit to compare resuscitation with lactated Ringer's solution, Haemaccel, whole blood, and diaspirin cross-linked hemoglobin following hemorrhage in rats.
Base deficit (BD) has been shown to be a sensitive measure of the degree and duration of inadequate perfusion. We developed a rat… 
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