succinylacetone

Known as: 4,6-dioxoheptanoic acid, Heptanoic acid, 4,6-dioxo- 
 
National Institutes of Health

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2008
2008
BACKGROUND Tyrosinemia type I (TYR 1) is a disorder causing early death if left untreated. Newborn screening (NBS) for this… (More)
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2006
2006
BACKGROUND False-positive and false-negative results occur in current newborn-screening programs for hepatorenal tyrosinemia… (More)
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2006
2006
BACKGROUND Tyrosinemia type I (TYR 1) is a severe disorder causing early death if left untreated. While tyrosine can be… (More)
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1998
1998
The glycolytic enzyme glyceraldehyde-3-phosphate dehydrogenase (GAPDH) is induced by hypoxia in endothelial cells (EC). To define… (More)
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1996
1996
Succinylacetone (SA) is an inhibitor of heme synthesis that acts on the enzyme delta-aminolevulinic acid dehydratase. When… (More)
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Highly Cited
1992
Highly Cited
1992
Liver transplantation is the only effective treatment for hereditary tyrosinaemia type I (McKusick 276700). We have treated one… (More)
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1982
1982
We have investigated the effect of succinylacetone (4,6-dioxoheptanoic acid) on hemoglobin synthesis and iron metabolism in… (More)
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1982
1982
A technique designed to measure quantitatively succinylacetone (4,6-dioxoheptanoic acid) is presented. It essentially involves… (More)
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1981
1981
Succinylacetone was excreted in the urine from four patients, with hereditary tyrosinemia i.e., two patients with the severe… (More)
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Highly Cited
1977
Highly Cited
1977
The activity of the enzyme porphobilinogen synthase (EC 4.2.1.24) in erythrocytes from patients with hereditary tyrosinemia was… (More)
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