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steryl-sulfatase activity

Known as: sterol sulfatase activity, dehydroepiandrosterone sulfate sulfatase activity, steryl-sulphatase activity 
Catalysis of the reaction: 3-beta-hydroxyandrost-5-en-17-one 3-sulfate + H2O = 3-beta-hydroxyandrost-5-en-17-one + sulfate. [EC:3.1.6.2]
National Institutes of Health

Papers overview

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2008
2008
An improved steroid sulfatase inhibitor was prepared by replacing the N-propyl group of the second-generation steroid-like… Expand
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2003
2003
The present study describes the biological in vitro and in vivo evaluation of 2-methoxy derivatives of estrogenic inhibitors of… Expand
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Highly Cited
1999
Highly Cited
1999
Steroid sulfates are precursors of hormones that stimulate androgen- and estrogen-dependent cancers. Thus, steroid sulfatase, the… Expand
Review
1996
Review
1996
 
Highly Cited
1995
Highly Cited
1995
The intent of the study was to determine whether altering the metabolism of neurosteroids via blockade of the enzyme, steroid… Expand
Highly Cited
1988
Highly Cited
1988
We isolated 12 strictly anaerobic steroid-3-sulfate-desulfating strains from the intestinal floras of rats and humans. Two… Expand
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Highly Cited
1984
Highly Cited
1984
The pathological scaling in recessive x-linked ichthyosis is associated with accumulation of abnormal quantities of cholesterol… Expand
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1984
1984
Abstract. The hydrolysis of dehydroepiandrosterone sulfate (DHAS) by human liver cells in culture and the hydrolysis of and… Expand
Highly Cited
1981
Highly Cited
1981
Patients with recessive X-linked ichthyosis, one of the inherited types of excessive stratum corneum cohesion, have deficient… Expand
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1973
1973
Previously, we have proposed that inhibition of human placental steroid sulfatase by endogenous steroids may render it rate… Expand