steroid 21-monooxygenase activity

Known as: 21-hydroxylase activity, steroid 21-hydroxylase activity, steroid,hydrogen-donor:oxygen oxidoreductase (21-hydroxylating) 
Catalysis of the reaction: a steroid + donor-H2 + O2 = a 21-hydroxysteroid + acceptor + H2O. [EC:1.14.99.10]
National Institutes of Health

Papers overview

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2002
2002
Dr. Deborah P. Merke (Warren Grant Magnuson Clinical Center, National Institutes of Health [NIH], Bethesda, Maryland): Congenital… (More)
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2000
2000
The 21-hydroxylation of 17alpha-hydroxyprogesterone is one step in the biosynthesis of corticosteroids. Both 7 days of handling… (More)
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1998
1998
The physiological importance of adrenal 21-hydroxylase cytochrome P450 (CYP21) expression is clearly demonstrated by 21… (More)
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1992
1992
The role of cytochrome b5 in adrenal microsomal steroidogenesis was studied in guinea pig adrenal microsomes and also in the… (More)
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1991
1991
The present study reports the case of a 25-yr-old man with congenital adrenal hyperplasia due to 21-hydroxylase deficiency in… (More)
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1990
1990
Congenital adrenal hyperplasia (CAH) is a common recessive genetic disease caused mainly by steroid 21-hydroxylase (P450c21… (More)
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1989
1989
21-Hydroxylase-deficient late-onset adrenal hyperplasia (LOAH) appears to affect 1-6% of hyperandrogenic women. Screening and… (More)
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1987
1987
Quantitative high-pressure liquid chromatographic assays were developed that separate progesterone and 17 authentic… (More)
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1982
1982
We measured deoxycorticosterone (DOC) and progesterone (P) in plasma of 47 women pregnant with a dead fetus and sequentially… (More)
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1981
1981
The plasma concentrations of dehydroepiandrosterone, androstenedione, and dehydroepiandrosterone sulfate decrease during the… (More)
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