Skip to search formSkip to main content
You are currently offline. Some features of the site may not work correctly.

steroid 21-monooxygenase activity

Known as: 21-hydroxylase activity, steroid 21-hydroxylase activity, steroid,hydrogen-donor:oxygen oxidoreductase (21-hydroxylating) 
Catalysis of the reaction: a steroid + donor-H2 + O2 = a 21-hydroxysteroid + acceptor + H2O. [EC:1.14.99.10]
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2002
Highly Cited
2002
Dr. Deborah P. Merke (Warren Grant Magnuson Clinical Center, National Institutes of Health [NIH], Bethesda, Maryland): Congenital… Expand
Is this relevant?
Highly Cited
2000
Highly Cited
2000
The 21-hydroxylation of 17alpha-hydroxyprogesterone is one step in the biosynthesis of corticosteroids. Both 7 days of handling… Expand
Is this relevant?
Highly Cited
1994
Highly Cited
1994
Cytochrome P450c17 is the single enzyme having steroid 17 alpha-hydroxylase and 17,20 lyase activities. We sought to model the… Expand
Is this relevant?
Highly Cited
1992
Highly Cited
1992
The role of cytochrome b5 in adrenal microsomal steroidogenesis was studied in guinea pig adrenal microsomes and also in the… Expand
Is this relevant?
Review
1992
Review
1992
  • P. White, M. New
  • The Journal of clinical endocrinology and…
  • 1992
  • Corpus ID: 9678801
Most cases of congenital adrenal hyperplasia, the inherited inability to synthesize cortisol, are caused by a deficiency of the… Expand
Is this relevant?
Highly Cited
1990
Highly Cited
1990
Congenital adrenal hyperplasia (CAH) is a common recessive genetic disease caused mainly by steroid 21-hydroxylase (P450c21… Expand
Is this relevant?
Highly Cited
1990
Highly Cited
1990
Recombinant plasmids for expression of bovine cytochrome P450c21 (pA gamma 2), both P450c21 and yeast NADPH-cytochrome P450… Expand
Is this relevant?
Highly Cited
1987
Highly Cited
1987
Quantitative high-pressure liquid chromatographic assays were developed that separate progesterone and 17 authentic… Expand
Is this relevant?
Highly Cited
1981
Highly Cited
1981
The plasma concentrations of dehydroepiandrosterone, androstenedione, and dehydroepiandrosterone sulfate decrease during the… Expand
  • table I
  • table II
  • figure 1
  • table III
Is this relevant?
Highly Cited
1981
Highly Cited
1981
In the two clinical syndromes of congenital adrenal hyperplasia due to a 21-hydroxylation defect of adrenal steroidogenesis, the… Expand
Is this relevant?