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stallimycin

Known as: DISTAMYCIN A, Herperetin, distamycin 
An oligopeptide antineoplastic antibiotic isolated from the bacterium Streptomyces distallicus. Distamycin preferentially binds to adenine-thymine (A… Expand
National Institutes of Health

Related topics

Related topics

3 relations

Broader (2)

Antiviral AgentsDistamycins
NCIt Antineoplastic Agent Terminology

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2006
Highly Cited
2006
Structures, spectra, and DNA-binding properties of mixed ligand copper(II) complexes of iminodiacetic acid: the novel role of diimine co-ligands on DNA conformation and hydrolytic and oxidative…
The coordination geometry around copper(II) in [Cu(imda)(phen)(H2O)] (1) (H2imda = iminodiacetic acid, phen = 1,10-phenanthroline… Expand
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Highly Cited
2001
Highly Cited
2001
A simple, high-resolution method for establishing DNA binding affinity and sequence selectivity.
Full details of the development of a simple, nondestructive, and high-throughput method for establishing DNA binding affinity and… Expand
Highly Cited
1999
Highly Cited
1999
Sequence and structural selectivity of nucleic acid binding ligands.
The sequence and structural selectivity of 15 different DNA binding agents was explored using a novel, thermodynamically rigorous… Expand
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Highly Cited
1993
Highly Cited
1993
GC base sequence recognition by oligo(imidazolecarboxamide) and C-terminus-modified analogues of distamycin deduced from circular dichroism, proton nuclear magnetic resonance, and…
The DNA binding properties of a series of imidazole-containing and C-terminus-modified analogues 4-7 of distamycin are described… Expand
Highly Cited
1993
Highly Cited
1993
The search for structure-specific nucleic acid-interactive drugs: effects of compound structure on RNA versus DNA interaction strength.
The RNA genomes of a number of pathogenic RNA viruses, such as HIV-1, have extensive folded conformations with imperfect A-form… Expand
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Highly Cited
1990
Highly Cited
1990
The A.T-DNA-binding domain of mammalian high mobility group I chromosomal proteins. A novel peptide motif for recognizing DNA structure.
We have determined the domains of the mammalian high mobility group (HMG)I chromosomal proteins necessary and sufficient for… Expand
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Highly Cited
1987
Highly Cited
1987
A bifurcated hydrogen-bonded conformation in the d(A.T) base pairs of the DNA dodecamer d(CGCAAATTTGCG) and its complex with distamycin.
The crystal structures of d(CGCA3T3GCG) complex to the antitumor drug distamycin and the DNA fragment alone were solved by x-ray… Expand
Review
1986
Review
1986
Nonintercalating DNA-binding ligands: specificity of the interaction and their use as tools in biophysical, biochemical and biological investigations of the genetic material.
II. DNA BINDING ANTIBIOTICS 1. Pyrrole-Amidine Antibiotics and Synthetic Analogues (a) Structure and physical properties (b… Expand
Highly Cited
1985
Highly Cited
1985
The molecular origin of DNA-drug specificity in netropsin and distamycin.
X-ray analysis of the complex of netropsin with the B-DNA dodecamer of sequence C-G-C-G-A-A-T-T-BrC-G-C-G reveals that the… Expand
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Highly Cited
1978
Highly Cited
1978
Modification of DAPI banding on human chromosomes by prestaining with a DNA-binding oligopeptide antibiotic, distamycin A.
Abstract A DNA-binding AT-specific oligopeptide antibiotic, distamycin A, was used as non-fluorescent counterstain in conjunction… Expand
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