squalene monooxygenase activity

Known as: squalene,NADPH:oxygen oxidoreductase (2,3-epoxidizing) activity, squalene-2,3-epoxidase activity, squalene oxydocyclase activity 
Catalysis of the reaction: H(+) + NADPH + O(2) + squalene = (S)-2,3-epoxysqualene + H(2)O + NADP(+). [RHEA:25285]
National Institutes of Health

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2015
2015
A lower serum cholesterol level was recently shown to be one of the causes of stroke in an epidemiological study. Spontaneously… (More)
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2005
2005
erg26-1ts cells harbor defects in the 4alpha-carboxysterol-C3 dehydrogenase activity necessary for conversion of 4,4… (More)
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2002
2002
In order to clarify that squalene monohydroperoxide (SQOOH) correlates with changes in morphology through cytotoxicity and… (More)
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1996
1996
Squalene epoxidase (SE) is the primary target of the allylamine antimycotic agents terbinafine and naftifine and also of the… (More)
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1991
1991
Ultraviolet irradiation is capable of affecting skin surface lipids, especially squalene and cholesterol, both in vitro and in… (More)
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1991
1991
Inclusion of 1.1% elemental tellurium in the diet of postweanling rats produces a peripheral neuropathy due to a highly… (More)
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1990
1990
Regulation of squalene epoxidase in the cholesterol biosynthetic pathway was studied in a human hepatoma cell line, HepG2 cells… (More)
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1990
1990
Regulation of squalene epoxidase activity was examined in rat hepatic microsomes. The hepatic squalene epoxidase activity was… (More)
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1987
1987
Squalene epoxidase activity has been studied in cell-free preparations of Chinese hamster ovary (CHO) cells and rat liver. In… (More)
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1983
1983
Supernatant protein factor (SPF), a protein that stimulates squalene epoxidation, mediates the transfer of squalene between two… (More)
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