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squalene monooxygenase activity

Known as: squalene,NADPH:oxygen oxidoreductase (2,3-epoxidizing) activity, squalene-2,3-epoxidase activity, squalene oxydocyclase activity 
Catalysis of the reaction: H(+) + NADPH + O(2) + squalene = (S)-2,3-epoxysqualene + H(2)O + NADP(+). [RHEA:25285]
National Institutes of Health

Papers overview

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2017
2017
Role of Squalene Epoxidase (SQLE) in promoting fatty liver disease-associated liver cancer
2005
2005
VIDVLTYLA SIHEQSTFQF LSDMTANALT HATDALVYLS QLKTQEYFNF LNELITNTLQ HIPDVLTYLS RLRNQSVFNF LNELITNALQ EIPDVITYLS RLRNQSVFNF LNELITNALH IIPDVITYLS RLRNQSVFNF LNEL
We have isolated and characterized two overlapping cDNA clones for Arabidopsis thaliana squalene synthase. Their nucleotide… 
2004
2004
Induction of CYP 3 A by 2 , 3-Oxidosqualene : Lanosterol Cyclase Inhibitors Is Mediated by an Endogenous Squalene Metabolite in Primary Cultured Rat Hepatocytes
The effects of inhibitors of 2,3-oxidosqualene:lanosterol cyclase (cyclase) on cytochrome P450 expression were investigated in… 
1999
1999
Pengaruh penggunaan arang aktif dan bentonit terhadap warna dan bau minyak hati ikan hiu (Squalene)
Minyak hati ikan hiu diperoleh dari hasil ekstraksi hati ikan hiu dengan kandungan squalene sangat tinggi (80-85%) sehingga… 
1995
1995
Pengaruh Dari Sediaan Yang Mengandung Squalene Dan Lecithin Tang Beredar Di Pasaran Terhadap Kadar Glukosa Darah Kelinci Normal Dengan Menggunakan Uji Tolerensi Glukosa Dan Tanpa Toleransi Glukosa…
Penelitian pengaruh sediaan campuran squalene (97,9%) dan lecithin (2, 1 %) terhadap kadar glukosa darah dilakukan pada 4 ekor… 
1983
1983
Intermembrane transfer of squalene promoted by supernatant protein factor.
Supernatant protein factor (SPF), a protein that stimulates squalene epoxidation, mediates the transfer of squalene between two… 
1983
1983
Absorption and metabolic fate of dietary3H-squalene in the rat
The absorption and metabolic fate of dietary squalene were investigated on the rat by administering a single oral dose of3H… 
1982
1982
[Emission spectral analysis of ultraweak chemiluminescence from linolenic acid and squalene peroxides (author's transl)].
1980
1980
A deficiency of mixed function oxidase activities in the cholesterol biosynthetic pathway of human granulocytes.
Highly purified human granulocytes synthesize [14C]farnesol and [14C]squalene but not [14C]sterols from [14C]mevalonic acid… 
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