sphingosine kinase

 
National Institutes of Health

Papers overview

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Highly Cited
2010
Highly Cited
2010
Lymphocyte egress from lymph nodes (LNs) is dependent on sphingosine-1-phosphate (S1P), but the cellular source of this S1P is… (More)
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Highly Cited
2006
Highly Cited
2006
Sphingosine kinase (SK) is an oncogenic sphingolipid-metabolizing enzyme that catalyzes the formation of the mitogenic second… (More)
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Highly Cited
2005
Highly Cited
2005
The potent sphingolipid metabolite sphingosine 1-phosphate is produced by phosphorylation of sphingosine catalyzed by sphingosine… (More)
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Highly Cited
2004
Highly Cited
2004
BACKGROUND Phosphorylation of sphingosine by sphingosine kinase (SK) is the rate-limiting step in the cellular synthesis of… (More)
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Highly Cited
2003
Highly Cited
2003
Sphingolipid-metabolizing enzymes control the dynamic balance of the cellular levels of bioactive lipids, including the… (More)
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Highly Cited
2003
Highly Cited
2003
The immunomodulatory drug FTY720 is phosphorylated in vivo, and the resulting FTY720 phosphate as a ligand for sphingosine-1… (More)
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Highly Cited
2003
Highly Cited
2003
There are two isoforms of sphingosine kinase (SphK) that catalyze the formation of sphingosine 1-phosphate, a potent sphingolipid… (More)
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Highly Cited
2002
Highly Cited
2002
Vascular endothelial growth factor (VEGF) signaling is critical to the processes of angiogenesis and tumor growth. Here, evidence… (More)
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Highly Cited
2000
Highly Cited
2000
Sphingosine kinase (SphK) is a highly conserved lipid kinase that phosphorylates sphingosine to form sphingosine-1-phosphate (S1P… (More)
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Highly Cited
2000
Highly Cited
2000
Sphingosine kinase (SK) catalyzes the formation of sphingosine 1-phosphate (S1P), a lipid messenger that plays an important role… (More)
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