sphingosine kinase-1

Known as: SPHK1 enzyme, SPK1 protein, human 
 
National Institutes of Health

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Highly Cited
2011
Highly Cited
2011
PURPOSE The present study was to examine the effect of sphingosine kinase-1 (SPHK1) on chemotherapeutics-induced apoptosis in non… (More)
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2010
2010
Sphingosine-1-phosphate (S1P) is an important bioactive sphingolipid involved in angiogenesis and lymphangiogenesis, 2 important… (More)
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2009
2009
We previously demonstrated that sphingosine kinase-1 (SphK1) is an important mediator in the cytoplasmic signaling of estrogens… (More)
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Highly Cited
2008
Highly Cited
2008
PURPOSE To characterize the expression of sphingosine kinase-1 (SPHK1) in human astrocytomas and to investigate the association… (More)
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Highly Cited
2008
Highly Cited
2008
AIMS Sphingosine-1-phosphate (S1P) plays a vital role in cytoskeletal rearrangement, development, and apoptosis. Sphingosine… (More)
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2008
2008
We examined the involvement of sphingosine kinase-1 (SphK1), which governs the ceramide/sphingosine-1-phosphate balance, in… (More)
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2008
2008
Endothelial cells (ECs) regulate the barrier function of blood vessels. Here we show that basal and angiopoietin-1 (Ang-1… (More)
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Highly Cited
2007
Highly Cited
2007
The mitochondrial enzyme monoamine oxidase (MAO), its isoform MAO-A, plays a major role in reactive oxygen species-dependent… (More)
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Highly Cited
2006
Highly Cited
2006
The transactivation of enhanced growth factor receptor (EGFR) by G protein-coupled receptor (GPCR) ligands is recognized as an… (More)
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Highly Cited
2005
Highly Cited
2005
Systemic chemotherapy was considered of modest efficacy in prostate cancer until the recent introduction of taxanes. We took… (More)
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