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sphingosine kinase-1

Known as: SPHK1 enzyme, SPK1 protein, human 
National Institutes of Health

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SPHK1 geneSphingosine Kinase 2, Humansphingosine kinase

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Sphingosine Kinase 1, Human

Papers overview

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2017
2017
Investigating the contribution of aberrant sphingosine 1-phosphate signalling to the pathogenesis of diffuse large B-cell lymphoma
There is an increasing body of evidence indicating an important role for the bioactive signalling lipid S1P (sphingosine 1… 
2017
2017
Mast Cells and Lipid Cross-Talk in Skin Inflammation
Atopic dermatitis (AD) is an inflammatory skin disease whose pathogenic mechanisms remain unclear. We describe a novel method of… 
2011
2011
Cancer Therapy : Preclinical Sphingosine Kinase-1 Enhances Resistance to Apoptosis through Activation of PI 3 K / Akt / NFk B Pathway in Human Non – Small Cell Lung Cancer
Purpose: The present study was to examine the effect of sphingosine kinase-1 (SPHK1) on chemotherapeutics-induced apoptosis in… 
2011
2011
Abstract 15655: Thrombin Induces Expression Of Sphingosine Kinase-1 (SPHK-1) In Human Vascular Smooth Muscle Cells Via The mRNA Stabilising Protein HuR. Inhibition By Dabigatran Reduces Vascular SPHK…
2009
2009
Sphingosine-1-Phosphate Regulates Glioblastoma Cell Invasiveness through the Urokinase Plasminogen Activator System and CCN 1 / Cyr 61
Glioblastoma multiforme (GBM) is an aggressively invasive brain neoplasm with poor patient prognosis. We have previously shown… 
2009
2009
Abstracts from the 7th International Meeting of the Sphingolipid Club held in Leiden, The Netherlands, 14.-16.11.2008
Abstracts from the 7th International Meeting of the Sphingolipid Club held in Leiden, The Netherlands, 14.-16.11.2008s from the… 
2007
2007
Regulation of Invasiveness of Glioblastoma Multiforme Cell Lines and Tumor Stem Cells by Sphingosine Kinase and Sphingosine 1-Phosphate Reveals Potential Molecular Therapeutic Targets
Glioblastoma Multiforme (GBM), the most common primary brain tumor in adult patients, is a grade IV astrocytic neoplasm… 
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