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sphingosine cholinephosphotransferase activity

Known as: cytidine diphosphocholine-sphingosine cholinephosphotransferase activity, CDP-choline:sphingosine cholinephosphotransferase activity, CDP-choline-sphingosine cholinephosphotransferase activity 
Catalysis of the reaction: CDP-choline + sphingosine = CMP + H(+) + sphingosyl-phosphocholine. [EC:2.7.8.10, RHEA:21227]
National Institutes of Health

Papers overview

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Highly Cited
2012
Highly Cited
2012
The Hippo pathway is crucial in organ size control, and its dysregulation contributes to tumorigenesis. However, upstream signals… Expand
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2010
2010
Ceramidase (CDase) catalyzes the hydrolysis of ceramide (Cer) to sphingosine (Sph) and fatty acid. We have reported the molecular… Expand
2008
2008
The authors describe a novel multi-lamellar concentrate based on ceramide technology and newly identified cell-signalling… Expand
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2006
2006
The intracellular distribution of synthetic glycosphingolipids (GSLs) bearing a fluorophore can be monitored in living cells by… Expand
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2005
2005
[Reaction: see text]. Reaction of chiral guanidinium ylides with alpha,beta-unsaturated aldehydes gives 3-(alpha,beta-unsaturated… Expand
Highly Cited
2003
Highly Cited
2003
An overexpression system was recently developed to produce and purify recombinant, human acid ceramidase. In addition to ceramide… Expand
Highly Cited
2001
Highly Cited
2001
We have previously purified a membrane-bound ceramidase from rat brain and recently cloned the human homologue. We also observed… Expand
Highly Cited
1995
Highly Cited
1995
Sphingosine has been shown to inhibit cell growth in many cell lines although the mechanism of this effect remains obscure. More… Expand
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1994
1994
The phospholipase D (PLD)-mediated synthesis of phosphatidylethanol (PtdEtOH) and the hydrolysis of phosphatidylethanolamine… Expand
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Highly Cited
1970
Highly Cited
1970
  • W. Stoffel
  • Chemistry and physics of lipids
  • 1970
  • Corpus ID: 27570775
Abstract Our studies in vivo and in vitro on the biosynthesis and the degradation of long chain sphingosine bases allow now to… Expand