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BackgroundProstate cancer (PCa) remains a challenge worldwide. Due to the development of castration-resistance, traditional first… Expand Dogs diagnosed with appendicular osteosarcoma typically succumb to metastatic disease within a year of diagnosis. The current… Expand A hallmark of long‐term memory formation is the requirement for protein synthesis. Administration of protein synthesis inhibitors… Expand AbstractPurposeHydroxychloroquine (HCQ), the analog of chloroquine, augments the effect of chemotherapies and radiotherapy on… Expand ABSTRACT Macroautophagy (hereafter autophagy) is a cellular catabolic process that is essential for maintaining tissue… Expand The inhibition of the mammalian target of rapamycin (mTOR) signaling pathway promotes the initiation of autophagy. Although it… Expand Imatinib mesylate (IM), a targeted competitive inhibitor of the BCR-ABL tyrosine kinase, has revolutionized the clinical… Expand ABSTRACT In selective autophagy, the adaptor protein SQSTM1/p62 plays a critical role in recognizing/loading cargo (e.g… Expand Vascular injury and chronic arterial diseases result in exposure of VSMCs (vascular smooth muscle cells) to increased… Expand Autophagy is an important intracellular catabolic mechanism that mediates the degradation of cytoplasmic proteins and organelles… Expand