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spautin-1

 
National Institutes of Health

Papers overview

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2019
2019
BackgroundProstate cancer (PCa) remains a challenge worldwide. Due to the development of castration-resistance, traditional first… Expand
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2018
2018
Dogs diagnosed with appendicular osteosarcoma typically succumb to metastatic disease within a year of diagnosis. The current… Expand
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2018
2018
We hypothesized that autophagy and associated lysosome function serve as a critical modulator during Nod-like receptor family… Expand
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2016
2016
ABSTRACT Macroautophagy (hereafter autophagy) is a cellular catabolic process that is essential for maintaining tissue… Expand
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2016
2016
The inhibition of the mammalian target of rapamycin (mTOR) signaling pathway promotes the initiation of autophagy. Although it… Expand
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2016
2016
Acute pancreatitis is characterized by zymogen preactivation. Severe inflammation caused by zymogen activation can eventually… Expand
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Highly Cited
2014
Highly Cited
2014
Imatinib mesylate (IM), a targeted competitive inhibitor of the BCR-ABL tyrosine kinase, has revolutionized the clinical… Expand
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2014
2014
ABSTRACT In selective autophagy, the adaptor protein SQSTM1/p62 plays a critical role in recognizing/loading cargo (e.g… Expand
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Highly Cited
2013
Highly Cited
2013
Vascular injury and chronic arterial diseases result in exposure of VSMCs (vascular smooth muscle cells) to increased… Expand
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Highly Cited
2011
Highly Cited
2011
Autophagy is an important intracellular catabolic mechanism that mediates the degradation of cytoplasmic proteins and organelles… Expand
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