spautin-1
National Institutes of Health
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Accumulating reports demonstrate that apoptosis does not explain all the effects of cancer therapy due to the innate and acquired…
A growing field of evidence suggests the involvement of oncogenic receptor tyrosine kinases (RTKs) in cell transformation…
PODOCYTE DEDIFFERENTIATION AND GLOMERULAR INJURY MEDIATED BY LYSOSOME DYSFUNCTION: ROLE OF ACID CERAMIDASE By Guangbi Li A…
Autophagy is a highly conserved lysosomal degradation process which can recycle unnecessary or dysfunctional cell organelles and…
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Trio (green) and F-actin (red) in an unstimulated axon growth cone (left) and one stimulated by netrin-1 (right…
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This time-lapse series shows that actin filaments “de-branch” in the presence of cortactin and PI(3,5)P2.
A…
Harvard and the Shanghai Institute of Organic Chemistry have identified a small molecule called spautin-1 that blocks the…