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The peptide hormone urocortin3 (Ucn3) is abundantly expressed by mature beta cells, yet its physiological role is unknown. Here… Expand Aims/hypothesisThe NEFA-responsive G-protein coupled receptor 120 (GPR120) has been implicated in the regulation of inflammation… Expand Pancreatic islets have a central role in blood glucose homeostasis. In addition to insulin-producing β-cells and glucagon… Expand OBJECTIVE
Ghrelin is a 28 amino acid residue peptide identified in both human and rat stomach and which acts as an endogenous… Expand To determine how arginine (Arg) stimulates GH secretion, we investigated its interaction with GHRH in vivo and in vitro. Six… Expand We studied the effect of truncated glucagon-like peptide-1 [naturally occurring GLP-1; proglucagon-(78-107) amide], a potent… Expand The interrelation between the secretion of two hypophysiotropic peptides, growth hormone-releasing factor (GRF) and somatostatin… Expand Growth hormone (GH) secretory patterns were studied in a patient with ectopic growth hormone releasing factor (GRF) secretion and… Expand The isolated vascularly perfused rat stomach was used to study the polarity, kinetics, and stoichiometry of gastrin and… Expand The effects of adrenergic substances on pancreatic insular secretions were studied in a completely isolated canine pancreas with… Expand