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solabegron

Known as: (R)-3'-((2-((2-(3-chlorophenyl)-2-hydroxyethyl)amino)ethyl)amino)-(1,1'-biphenyl)-3-carboxylic acid, 3'-((2-((2-(3-Chlorophenyl)-2-hydroxyethyl)amino)ethyl)amino)-(1,1'-biphenyl)-3-carboxylic Acid 
 
National Institutes of Health

Papers overview

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Review
2016
Review
2016
β3-Adrenoceptor agonists were originally considered as a promising drug class for the treatment of obesity and/or type 2 diabetes… Expand
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Review
2016
Review
2016
ABSTRACT Introduction: Drugs which prevent acetylcholine mediated involuntary detrusor contractions are the mainstay of… Expand
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2015
2015
A novel methodology to produce highly enantioenriched N-(2-ethylamino)-β-amino alcohols was developed. These compounds were… Expand
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Highly Cited
2012
Highly Cited
2012
BACKGROUND β-Adrenoceptor agonists are effective in animal models of bladder dysfunction, and the human bladder primarily… Expand
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2012
2012
The relaxant effect of an aryloxypropanolamine β3-adrenoceptor agonist on carbachol pre-contracted human detrusor muscle strips… Expand
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2010
2010
BACKGROUND & AIMS beta3 Adrenoceptor (beta3-AR) is expressed on adipocytes and enteric neurons. GW427353 is a human selective… Expand
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2009
2009
PURPOSE We investigated the presence of functional Beta1, Beta2 and Beta3-adrenoceptor in urothelium and detrusor muscle of human… Expand
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2008
2008
beta(3)-Adrenoceptors(beta(3)-AR) are expressed by cholinergic myenteric neurons and beta(3)-AR agonists are effective in… Expand
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Highly Cited
2007
Highly Cited
2007
Functional studies have demonstrated that adrenoceptor agonist-evoked relaxation is mediated primarily by β3-adrenergic receptors… Expand
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2004
2004
agonists as viable antiobestic or antidiabetic agents with improved potency are pursued. Most of β3-AR agonists tested in… Expand
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