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snRNP Biogenesis

The 4 major small nuclear ribonucleoprotein particles (snRNPs), U1, U2, U4/U6, and U5, share 8 proteins which form the snRNP structural core: SNRPB… 
National Institutes of Health

Related topics

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3 relations
SNRPF geneSNRPF wt AlleleSmall Nuclear Ribonucleoprotein Polypeptide F

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
Quality control in snRNP biogenesis
2015
2015
Note 1: Rap-ms Identifies Known U1 Snrna Interacting Proteins. Note 2: Validation of the Xist Interacting Proteins Identified by Rap-ms
We validated the RAP-MS approach by defining the proteins that interact with two wellcharacterized non-coding RNAs: (i) U1 small… 
2015
2015
Synaptic Vesicles, Mitochondria, and Actin Alterations in SMN-deficient Mice
Proximal spinal muscular atrophy (SMA) is an autosomal recessive disorder characterized by degeneration of the second motor… 
2012
2012
Reorganization of Cajal bodies and nucleolar targeting of coilin in motor neurons of type I spinal muscular atrophy
Type I spinal muscular atrophy (SMA) is an autosomal recessive disorder caused by loss or mutations of the survival motor neuron… 
2011
2011
Study into a role for Aar2p in U5 snRNP biogenesis
Aar2p is an essential yeast protein involved in pre-mRNA splicing and component of a U5 snRNP precursor form. It has been… 
2010
2010
Molecular Determinants of Survival Motor Neuron (SMN) Protein Cleavage by the Calcium-Activated Protease, Calpain
Spinal muscular atrophy (SMA) is a leading genetic cause of childhood mortality, caused by reduced levels of survival motor… 
2006
2006
ArticleThe Gemin 5 Protein of the SMN Complex Identifies snRNAs
The survival of motor neurons protein (SMN) is part of a large complex that contains six other proteins, Gemins2–7. The SMN… 
2000
2000
Exclusion of Htra2-β1, an up-regulator of full-length SMN2 transcript, as a modifying gene for spinal muscular atrophy
Spinal muscular atrophy (SMA) is a neurodegenerative disease caused by homozygous mutations of the survival motor neuron gene 1… 
1998
1998
Yeast Pre-mRNA Splicing Requires a Pair of U1 snRNP-Associated Tetratricopeptide Repeat Proteins
ABSTRACT The U1 snRNP functions to nucleate spliceosome assembly on newly transcribed pre-mRNA. Saccharomyces cerevisiae is… 
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