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small nuclear ribonucleoprotein complex location

Known as: small nuclear ribonucleoprotein complex, small nuclear ribonucleoprotein, snRNP location 
A complex composed of RNA of the small nuclear RNA (snRNA) class and protein, found in the nucleus of a eukaryotic cell. These are typically named… Expand
National Institutes of Health

Related topics

Related topics

2 relations
LSM2 geneSmall Nuclear Ribonucleoproteins

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2013
Highly Cited
2013
U1 small nuclear ribonucleoprotein complex and RNA splicing alterations in Alzheimer’s disease
  • B. Bai, C. Hales, +31 authors J. Peng
  • Proceedings of the National Academy of Sciences
  • 2013
    • Corpus ID: 12114747
Deposition of insoluble protein aggregates is a hallmark of neurodegenerative diseases. The universal presence of β-amyloid and… Expand
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Highly Cited
2011
Highly Cited
2011
Two-pronged Binding with Bromodomain-containing Protein 4 Liberates Positive Transcription Elongation Factor b from Inactive Ribonucleoprotein Complexes*
Background: P-TEFb interacts with BRD4, but the precise interaction domain is controversial. Results: The P-TEFb-interacting… Expand
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Highly Cited
2005
Highly Cited
2005
The Prp19-associated Complex Is Required for Specifying Interactions of U5 and U6 with Pre-mRNA during Spliceosome Activation*
Activation of the spliceosome involves a major structural change in the spliceosome, including release of U1 and U4 small nuclear… Expand
Highly Cited
1997
Highly Cited
1997
A protein related to splicing factor U2AF35 that interacts with U2AF65 and SR proteins in splicing of pre-mRNA
Recognition of a functional 3′ splice site in pre-mRNA splicing requires a heterodimer of the proteins U2AF65/U2AF35. U2AF65… Expand
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Highly Cited
1997
Highly Cited
1997
Identification of the proteins of the yeast U1 small nuclear ribonucleoprotein complex by mass spectrometry.
Here we report the rapid identification of the proteins of the spliceosomal U1 small nuclear ribonucleoprotein (snRNP) from the… Expand
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Highly Cited
1997
Highly Cited
1997
Identification and Characterization of a Nuclease Specific for the 3′ End of the U6 Small Nuclear RNA*
The U6 small nuclear RNA is post-transcriptionally processed by the addition and removal of nontemplate uridylates (Us) at its 3… Expand
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Highly Cited
1995
Highly Cited
1995
Distinct functions of SR proteins in recruitment of U1 small nuclear ribonucleoprotein to alternative 5' splice sites.
  • A. Zahler, M. Roth
  • Proceedings of the National Academy of Sciences…
  • 1995
    • Corpus ID: 30953440
Alternative splicing of precursor messenger RNAs (pre-mRNAs) is an important mechanism for the regulation of gene expression. The… Expand
Highly Cited
1990
Highly Cited
1990
Quantitative determination that one of two potential RNA-binding domains of the A protein component of the U1 small nuclear ribonucleoprotein complex binds with high affinity to stem-loop II of U1…
Many RNA-associated proteins contain a ribonucleoprotein (RNP) consensus octamer encompassed by a conserved 80 amino acid… Expand
1989
1989
Evidence from complementation assays in vitro that U5 snRNP is required for both steps of mRNA splicing.
We have established an in vitro complementation system that has allowed us to investigate the role of individual purified snRNPs… Expand
1985
1985
A murine monoclonal antibody recognizes the 13,000 molecular weight polypeptide of the Sm small nuclear ribonucleoprotein complex.
Antibodies to the Sm antigen are closely associated with the rheumatic disease systemic lupus erythematosus (SLE). The Sm antigen… Expand
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