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site of double-strand break

Known as: DNA damage foci, site of DSB, DNA damage focus 
A region of a chromosome at which a DNA double-strand break has occurred. DNA damage signaling and repair proteins accumulate at the lesion to… 
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
Diagnosis of Pain in the Right Iliac Fossa. A New Diagnostic Score Based on Decision-Tree and Artificial Neural Network Methods
2017
2017
Experimental detection of steerability in Bell local states with two measurement settings
Steering, a quantum property stronger than entanglement but weaker than non-locality in the quantum correlation hierarchy, is a… 
2016
2016
Comparison of the Radiosensitizing Effect of ATR, ATM and DNA-PK Kinase Inhibitors on Cervical Carcinoma Cells.
Here, we compared the effects of inhibitors of three phosphatidylinositol-3-kinase-related kinases, ATM, ATR a DNA-PK, on… 
2012
2012
Cleavage of the BRCT tandem domains of nibrin by the 657del5 mutation affects the DNA damage response less than the Arg215Trp mutation
The Nijmegen breakage syndrome (NBS) is a genetic disorder caused by mutations in NBN gene and characterized by chromosomal… 
2012
2012
Co-mutation of histone H2AX S139A with Y142A rescues Y142A-induced ionising radiation sensitivity
2011
2011
The ATM kinase signaling induced by the low-energy β-particles emitted by (33)P is essential for the suppression of chromosome aberrations and is greater than that induced by the energetic…
2007
2007
Association of DNA-PK activity and radiation-induced NBS1 foci formation in lymphocytes with clinical malignancy in breast cancer patients.
DNA double-strand break (DSB) is one of the most deleterious lesions induced by DNA damaging agents. DSB repair pathway is… 
Highly Cited
2006
Highly Cited
2006
E2F1 induces MRN foci formation and a cell cycle checkpoint response in human fibroblasts
Deregulation of the Rb/E2F pathway in human fibroblasts results in an E2F1-mediated apoptosis dependent on Atm, Nbs1, Chk2 and… 
2005
2005
NFBD 1 / Mdc 1 Mediates ATR-Dependent DNA Damage Response
Budding yeast Rad9 (scRad9) plays a central role in mediating Mec1-dependent phosphorylation by recruiting its downstream… 
1965
1965
Mechanism of Polykaryocytosis Associated with Noncytopathic Infection by Measles Virus
Atherton, John G. (University of Southern California, Los Angeles), Sotiros G. Chaparas, Martha Cremer, and Irving Gordon… 
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