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sirtinol
Â
National Institutes of Health
Topic mentions per year
Topic mentions per year
2002-2018
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10
20
30
2002
2018
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Broader (2)
Benzamides
Naphthols
Related mentions per year
Related mentions per year
1940-2018
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sirtinol
Naphthols
Benzamides
Papers overview
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2012
2012
Trichostatin A and sirtinol suppressed survivin expression through AMPK and p38MAPK in HT29 colon cancer cells.
Ya-Fen Hsu
,
Joen-Rong Sheu
,
+7 authors
Ming-Jen Hsu
Biochimica et biophysica acta
2012
BACKGROUND Elevated levels of survivin and histone deacetylases (HDACs) are often found over-expressed in human cancers…Â
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2012
2012
Sirtinol, a class III HDAC inhibitor, induces apoptotic and autophagic cell death in MCF-7 human breast cancer cells.
Jing Wang
,
Tae Hyung Kim
,
+7 authors
Hyung Sik Kim
International journal of oncology
2012
Sirtuins (SIRTs), NAD+-dependent class III histone deacetylases (HDACs), play an important role in the regulation of cell…Â
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2012
2012
High expression of the longevity gene product SIRT1 and apoptosis induction by sirtinol in adult T-cell leukemia cells.
Tomohiro Kozako
,
Akiyoshi Aikawa
,
+8 authors
Shinji Soeda
International journal of cancer
2012
Adult T-cell leukemia-lymphoma (ATL) is an aggressive peripheral T-cell neoplasm that develops after long-term infection with…Â
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2011
2011
Sirtinol Treatment Reduces Inflammation in Human Dermal Microvascular Endothelial Cells
Angela Orecchia
,
Claudia Scarponi
,
+9 authors
Cristina Maria Failla
PloS one
2011
Histone deacetylases (HDAC) are key enzymes in the epigenetic control of gene expression. Recently, inhibitors of class I and…Â
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Highly Cited
2009
Highly Cited
2009
Resveratrol pretreatment protects rat brain from cerebral ischemic damage via a sirtuin 1-uncoupling protein 2 pathway.
David Della-Morte
,
Keron Dave
,
Rossella Defazio
,
Yongmei Bao
,
A. P. Raval
,
Miguel A. Pérez-Pinzón
Neuroscience
2009
Resveratrol is a natural polyphenol found in grapes and wine and has been associated with protective effects against…Â
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Highly Cited
2007
Highly Cited
2007
Sirt1 modulates premature senescence-like phenotype in human endothelial cells.
Hidetaka Ota
,
Masahiro Akishita
,
Masato Eto
,
Katsuya Iijima
,
Masao Kaneki
,
Yasuyoshi Ouchi
Journal of molecular and cellular cardiology
2007
Yeast Sir2 plays critical roles in gene silencing, stress resistance and longevity. Mammalian Sirt1 NAD(+)-dependent protein…Â
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Highly Cited
2006
Highly Cited
2006
Resveratrol mimics ischemic preconditioning in the brain.
Ami P. Raval
,
Kunjan R. Dave
,
Miguel A. Pérez-Pinzón
Journal of cerebral blood flow and metabolism…
2006
Recent studies in a variety of species including mammals showed that resveratrol (trans-3, 5, 4''-trihydroxystibene) treatment…Â
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2005
2005
Design, synthesis, and biological evaluation of sirtinol analogues as class III histone/protein deacetylase (Sirtuin) inhibitors.
Antonello Mai
,
Silvio Massa
,
+7 authors
David A. Sinclair
Journal of medicinal chemistry
2005
In a search for potent inhibitors of class III histone/protein deacetylases (sirtuins), a series of sirtinol analogues have been…Â
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2005
2005
Genetic and chemical analyses of the action mechanisms of sirtinol in Arabidopsis.
Xinhua Dai
,
Ken-Ichiro Hayashi
,
Hiroshi Nozaki
,
Youfa Cheng
,
Yunde Zhao
Proceedings of the National Academy of Sciences…
2005
The synthetic molecule sirtinol was shown previously to activate the auxin signal transduction pathway. Here we present a…Â
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Highly Cited
2004
Highly Cited
2004
Silent information regulator 2alpha, a longevity factor and class III histone deacetylase, is an essential endogenous apoptosis inhibitor in cardiac myocytes.
Ralph R. Alcendor
,
Lorrie A. Kirshenbaum
,
Shin-ichiro Imai
,
Stephen F. Vatner
,
Junichi Sadoshima
Circulation research
2004
Yeast silent information regulator 2 (Sir2), a nicotinamide adenine dinucleotide-dependent histone deacetylase (HDAC) and…Â
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