signalosome

 
National Institutes of Health

Topic mentions per year

Topic mentions per year

1998-2018
05101519982018

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2008
2008
Constitutive activation of the NF-κB pathway by the Tax oncoprotein plays a crucial role in the proliferation and transformation… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Highly Cited
2005
Highly Cited
2005
Apoptosis signal-regulating kinase 1 (ASK1) plays a pivotal role in oxidative stress-induced cell death. Reactive oxygen species… (More)
Is this relevant?
Highly Cited
2003
Highly Cited
2003
The signalosome is implicated in regulating cullin-dependent ubiquitin ligases. We find that two signalosome subunits, Csn1 and… (More)
Is this relevant?
2003
2003
The COP9 signalosome (CSN) is a conserved multiprotein complex involved in regulation of eukaryotic development. The deduced… (More)
Is this relevant?
Highly Cited
2002
Highly Cited
2002
The COP9/signalosome complex is highly conserved in evolution and possesses significant structural similarity to the 19S… (More)
  • table 1
  • figure 1
  • figure 2
  • figure 3
  • table 2
Is this relevant?
2002
2002
The COP9 signalosome (CSN) is a complex of eight proteins first identified as a repressor of plant photomorphogenesis. A protein… (More)
Is this relevant?
Highly Cited
2001
Highly Cited
2001
The COP9 signalosome is an evolutionary conserved multiprotein complex of unknown function that acts as a negative regulator of… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
Is this relevant?
2001
2001
The transcription factor nuclear factor-kappaB (NF-kappaB) is activated by a diverse number of stimuli including tumor necrosis… (More)
Is this relevant?
Highly Cited
2000
Highly Cited
2000
The adapter protein RIP plays a crucial role in NF-kappaB activation by TNF. Here we show that triggering of the p55 TNF receptor… (More)
Is this relevant?
Highly Cited
1999
Highly Cited
1999
The basic region-leucine zipper transcription factor c-Jun regulates gene expression and cell function. It participates in the… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?