sialosyl-Tn antigen

Known as: NeuAc-alpha(2-6)-GalNAc-alpha-O-Ser(Thr), tumor-associated O-linked sialosyl-2--6 alpha-N-acetylgalactosaminyl antigen, Sialyl Tn antigen 
A tumor-associated core-region carbohydrate antigen of epithelial mucin, expressed in most colon carcinoma, mucinous carcinoma, pancreatic cancer… (More)
National Institutes of Health

Papers overview

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Review
1997
Review
1997
No abstract Abbreviations: Sia, sialic acid, type unspecified; Tn antigen, GalNAcα 1-O-Ser/Thr; T antigen, Galβ1-3GalNAcα-O-Ser… (More)
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1996
1996
BACKGROUND & AIMS Expression of the carbohydrate-associated sialosyl-Tn (STn) antigen has been correlated with carcinogenesis in… (More)
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Highly Cited
1993
Highly Cited
1993
The carbohydrate antigen, sialyl Lex, is known to be a ligand for the cell adhesion molecule called ELAM-1 (E-selectin… (More)
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1993
1993
We examined immunohistochemically the expression of sialosyl-Tn antigen (STN) in 137 primary gastric carcinomas. In the non… (More)
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1992
1992
Sialosyl-Tn antigen and its immediate precursor, Tn antigen, are carbohydrate structures associated with the earliest steps of… (More)
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1992
1992
In normal adult human tissues, sialosyl-Tn antigen, detected by monoclonal antibody TKH2, was uniformly found in the bronchus… (More)
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1992
1992
Immunohistochemical study of the expression of simple mucin-type carbohydrate antigens (Tn, sialosyl-Tn, T and sialosyl-T) was… (More)
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Highly Cited
1992
Highly Cited
1992
P-selectin (CD62, GMP-140, PADGEM), a Ca(2+)-dependent lectin on activated platelets and endothelium, functions as a receptor for… (More)
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Highly Cited
1990
Highly Cited
1990
Colon cancers typically produce mucin. However, it is not known whether tumor mucin plays a biological role in cancer cell… (More)
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Highly Cited
1988
Highly Cited
1988
Two monoclonal antibodies, TKH1 and TKH2, directed toward the sialosyl-Tn structure (NeuAc alpha 2----6GalNAc alpha 1----O-Ser or… (More)
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