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serine protease inhibitor complex
Known as:
serpin complex
, serine-type endopeptidase inhibitor complex location
, serine protease inhibitor complex location
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A heterodimeric protein complex that contains a serine protease inhibitor and a protease; formation of the complex inhibits serine protease activity…
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National Institutes of Health
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2004
2004
Kinetic mechanism of protease inhibition by alpha1-antitrypsin.
Un-Beom Kang
,
Je-Hyun Baek
,
Seung-Hyun Ryu
,
Joonhee Kim
,
Myeong-Hee Yu
,
Cheolju Lee
Biochemical and Biophysical Research…
2004
Corpus ID: 38389537
The native form of serine protease inhibitor (serpin) is kinetically trapped in a metastable state. Metastability in these…
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2002
2002
Kinetic dissection of alpha 1-antitrypsin inhibition mechanism.
J. Shin
,
Myeong-Hee Yu
Journal of Biological Chemistry
2002
Corpus ID: 25193174
Serpins (serine protease inhibitors) inhibit target proteases by forming a stable covalent complex in which the cleaved reactive…
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2001
2001
Conformational Changes in Thrombin When Complexed by Serpins*
J. Fredenburgh
,
A. Stafford
,
J. Weitz
Journal of Biological Chemistry
2001
Corpus ID: 36403351
Thrombin possesses two positively charged surface domains, termed exosites, that orient substrates and inhibitors for reaction…
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1999
1999
Ligand Binding Properties of the Very Low Density Lipoprotein Receptor
P. Rettenberger
,
K. Oka
,
+7 authors
P. Andreasen
Journal of Biological Chemistry
1999
Corpus ID: 24073434
The very low density lipoprotein receptor (VLDLR) binds, among other ligands, the M r 40,000 receptor-associated protein (RAP…
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