serine hydrolase activity

Catalysis of the hydrolysis of a substrate by a catalytic mechanism that involves a catalytic triad consisting of a serine nucleophile that is… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1995-2017
012319952017

Papers overview

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2018
2018
The release of aromatic amines from drugs and other xenobiotics resulting from the hydrolysis of metabolically labile amide bonds… (More)
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2016
2016
At the intestinal stage of a Trichinella spiralis (T. spiralis) infection, the excretory-secretory (ES) antigens produced by… (More)
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2015
2015
In mammalian brain, monoacylglycerol lipase (MAGL) is the primary enzyme responsible for terminating signaling function of the… (More)
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2013
2013
Serine hydrolases constitute a large enzyme family involved in a diversity of proteolytic and metabolic processes which are… (More)
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Review
2012
Review
2012
Human retinoblastoma binding protein 9 (RBBP9) is an interacting partner of the retinoblastoma susceptibility protein (Rb). RBBP9… (More)
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2010
2010
Pancreatic cancer is one of the most lethal malignancies. To discover functionally relevant modulators of pancreatic neoplasia… (More)
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2010
2010
Carboxylesterases (CES) have important roles in pesticide and drug metabolism and contribute to the clearance of ester-containing… (More)
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2005
2005
The Crt1 (RFX1) protein in Saccharomyces cerevisiae is an effector of the DNA damage checkpoint pathway. It recognizes a 13-bp… (More)
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Highly Cited
2001
Highly Cited
2001
Serine hydrolases represent one of the largest and most diverse families of enzymes in higher eukaryotes, comprising numerous… (More)
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1995
1995
Patatin, the nonspecific lipid acyl hydrolase from potato (Solanum tuberosum L.) tubers, dose-dependently inhibits the growth of… (More)
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