separase-securin complex

Known as: Cut1-2 complex, Cut1-2 complex location, separase-securin complex location 
A protein complex that includes separase and securin as components and that inhibits chromosome separation at mitosis. [GOC:dos, GOC:vw, PMID:8978688… (More)
National Institutes of Health

Papers overview

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Review
2018
Review
2018
The cysteine protease separase opens the cohesin ring by cleaving its kleisin subunit and is a pivotal cell cycle factor for the… (More)
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2017
2017
Separases are crucial cell cycle proteases that control the metaphase-to-anaphase transition by cleaving chromosomal cohesin… (More)
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2016
2016
The protease separase plays a key role in sister chromatid disjunction and centriole disengagement. To maintain genomic stability… (More)
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2014
2014
PTTG1 protein, the human securin, has a central role in sister chromatid separation during mitosis, and its altered expression… (More)
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2014
2014
Background:Cdc20 is an essential component of cell division and responsible for anaphase initiation regulated by securin… (More)
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Review
2013
Review
2013
Cell cycle regulators cdc27 and securin participate in control of the mitotic checkpoint and survey the mitotic spindle to… (More)
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2009
2009
Background:Securin is a recently recognised oncogene with multiple known functions in initiation, progression and cell cycle… (More)
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2007
2007
THE STICKING POINT: HUMAN RIGHTS AND CIVIL-MILITARY RELATIONS IN LATIN AMERICA LEBRUARY 2007 REBECCA K. ROOT. B.A.. ECKERD… (More)
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2005
2005
Accurate partition of duplicated genetic material to the daughter cells during mitosis relies on the maintenance of the physical… (More)
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2002
2002
BACKGROUND The separase-securin complex is required for anaphase. Separase activated by securin destruction cleaves the cohesin… (More)
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