senecionine

Known as: 12-hydroxysenecionan-11,16-dione 
 
National Institutes of Health

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2014
2014
Pyrrolizidine alkaloids (PAs) are among the most hepatotoxic natural products that produce irreversible injury to humans via the… (More)
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2004
2004
Root cultures of Senecio erucifolius (Asteraceae) efficiently took up and incorporated [14C]putrescine and [14C]arginine into the… (More)
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1998
1998
Laboratory and field tracer experiments with 14C-labelled senecionine N–oxide (SO) and distant biosynthetic precursors such as… (More)
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Highly Cited
1997
Highly Cited
1997
Larvae of Creatonotos transiens (Lepidoptera, Arctiidae) and Zonocerus variegatus (Orthoptera, Pyrgomorphidae) ingest 14C-labeled… (More)
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1991
1991
Studies were carried out to investigate the metabolism of senecionine by human liver microsomes and the role of human cytochrome… (More)
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1991
1991
Evidence based on optimal pH, thermal stability, and enzyme inhibition data suggests that the NADPH-dependent microsomal N… (More)
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1989
1989
Rats display a marked sex difference in the oxidation of the pyrrolizidine alkaloid senecionine, especially with respect to N… (More)
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1989
1989
The pyrrolizidine alkaloid, senecionine, is N-oxidized by purified pig liver flavin-containing monooxygenase but not by purified… (More)
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1988
1988
The MeOH extract of Senecio vulgaris L., administered po to rats on Days 1-10 postcoitum, significantly decreased the number of… (More)
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1985
1985
The toxicity of macrocyclic pyrrolizidine alkaloids in the livers of man and animals has been attributed to the formation of… (More)
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