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selegiline hydrochloride

Known as: Hydrochloride, Selegiline, Selegiline Hydrochloride, (R)-Isomer [Chemical/Ingredient], L-deprenyl Hydrochloride 
The hydrochloride salt form of selegiline, a levorotatory acetylenic derivative of phenethylamine with antiparkinsonian effect. As a selective… Expand
National Institutes of Health

Papers overview

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2015
2015
Selegiline (L-deprenyl) is a selective, irreversible inhibitor of monoamine oxidase B (MAO-B) at the conventional dose (10 mg/day… Expand
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Review
2007
Review
2007
Inhibitors of monoamine oxidase (MAO) with selectivity and specificity for MAO type B prolong the activity of both endogenously… Expand
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2007
2007
We have earlier shown that α-methylated spermidine and spermine analogues rescue cells from polyamine depletion-induced growth… Expand
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Highly Cited
2003
Highly Cited
2003
Summary. Seven randomised comparative studies were conducted in healthy volunteers to compare the pharmacokinetic and… Expand
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Highly Cited
2003
Highly Cited
2003
BACKGROUND Since dopaminergic mechanisms appear to be involved in nicotine dependence, we studied the safety and efficacy of the… Expand
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2003
2003
Summary. Three studies were performed using a fast dissolving formulation of selegiline hydrochloride designed for buccal… Expand
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2003
2003
DNA strand breaks induced by alkylating agents, oxidants or ionizing radiation trigger the covalent modification of nuclear… Expand
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2001
2001
Six hundred forty-one dogs with clinical signs consistent with canine cognitive dysfunction syndrome (CDS) were treated orally… Expand
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Highly Cited
1999
Highly Cited
1999
The effect of subchronic treatment with L-dopa/carbidopa or L-selegiline on striatal dopamine transporters (DAT) was examined in… Expand
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Highly Cited
1997
Highly Cited
1997
  • Heung Sup Shin
  • Drug metabolism and disposition: the biological…
  • 1997
  • Corpus ID: 1610441
Nine urinary metabolites of selegiline hydrochloride [N-methyl-N-propargyl [2-phenyl-1-methyl)ethylammonium chloride], a… Expand
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