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sangivamycin

Known as: 4-amino-5-carboxamido-7-(D-ribofuranosyl)-pyrrolo-(2,3-d)pyrimidine 
 
National Institutes of Health

Papers overview

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Highly Cited
2008
Highly Cited
2008
Pyrrolopyrimidine nucleosides analogs, collectively referred to as deazapurines, are an important class of structurally diverse… Expand
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Highly Cited
2003
Highly Cited
2003
We used synthetic lethal high-throughput screening to interrogate 23,550 compounds for their ability to kill engineered… Expand
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Highly Cited
1995
Highly Cited
1995
Sublethal concentrations of reactive oxygen intermediates including H2O2 can alter human T cell function and inhibit… Expand
Highly Cited
1992
Highly Cited
1992
Protein kinase C (PKC) is activated rapidly and transiently following ionizing radiation exposure and is postulated to activate… Expand
1989
1989
During the screening for the inhibitors of protein kinase C (PKC), we found that a streptomycete produced an inhibitor in our… Expand
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1989
1989
A number of 7-[(2-hydroxyethoxy)methyl]pyrrolo[2,3-d]pyrimidine derivatives related to the nucleoside antibiotics toyocamycin and… Expand
Highly Cited
1989
Highly Cited
1989
A number of 7-[(1,3-dihydroxy-2-propoxy)methyl]pyrrolo[2,3d-d]pyrimidine derivatives that are structurally related to toyocamycin… Expand
Highly Cited
1988
Highly Cited
1988
Protein kinase C functions prominently in cell regulation via its pleiotropic role in signal transduction processes. Certain… Expand
Highly Cited
1987
Highly Cited
1987
Seven arabinosyl, 2'-deoxyribosyl, and ribosyl pyrrolo[2,3-d]pyrimidines were evaluated in vitro for activity against human… Expand
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Highly Cited
1987
Highly Cited
1987
Treatment of 7-amino-3-beta-D-ribofuranosylpyrazolo[4,3-d]pyrimidine (formycin) with alpha-acetoxyisobutyryl bromide followed by… Expand