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sangivamycin

Known as: 4-amino-5-carboxamido-7-(D-ribofuranosyl)-pyrrolo-(2,3-d)pyrimidine 
National Institutes of Health

Related topics

Related topics

4 relations

Broader (3)

Anti-Bacterial AgentsAntibiotics, AntineoplasticPyrimidine Nucleosides

Narrower (1)

NSC 65346

Papers overview

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1991
1991
Differential effects of pertussis toxin on insulin-stimulated phosphatidylcholine hydrolysis and glycerolipid synthesis de novo. Studies in BC3H-1 myocytes and rat adipocytes.
Insulin-induced increases in diacylglycerol (DAG) have been suggested to result from stimulation of de novo phosphatidic acid (PA… 
1989
1989
Synthesis, cytotoxicity, and antiviral activity of certain 7-[(2-hydroxyethoxy)methyl]pyrrolo[2,3-d]pyrimidine nucleosides related to toyocamycin and sangivamycin.
A number of 7-[(2-hydroxyethoxy)methyl]pyrrolo[2,3-d]pyrimidine derivatives related to the nucleoside antibiotics toyocamycin and… 
1983
1983
Pyrrolopyrimidine nucleosides. 18. Synthesis and chemotherapeutic activity of 4-amino-7-(3-deoxy-beta-D-ribofuranosyl)pyrrolo[2,3-d] pyrimidine-5-carboxamide (3'-deoxysangivamycin) and 4-amino-7-(2…
A multistep synthesis, using the nucleoside antibiotic toyocamycin as the starting material, has furnished 6,2'-S… 
1983
1983
2',5'-Oligoadenylates and related 2',5'-oligonucleotide analogues. 1. Substrate specificity of the interferon-induced murine 2',5'-oligoadenylate synthetase and enzymatic synthesis of oligomers.
The substrate specificity of the interferon-induced mouse L-cell enzyme, 2',5'-oligoadenylate synthetase, was determined with a… 
1983
1983
2',5'-Oligoadenylates and related 2',5'-oligonucleotide analogues. 2. Effect on cellular proliferation, protein synthesis, and endoribonuclease activity.
A number of the new enzymatically synthesized 2',5'-oligonucleotide trimers, namely, those containing the nucleosides 8… 
1981
1981
Kinetic effects of sangivamycin in sarcoma 180 in vitro.
The lethal and sublethal effects of sangivamycin (SGM) were studied in sarcoma 180 in vitro in relation to drug concentration and… 
1981
1981
Biosynthesis of the Nucleoside Antibiotics
About seventy naturally occurring nucleoside analogs have been isolated to date. As with the numerous other analog types that… 
1977
1977
Pyridopyrimidines.7. Ribonucleosides structurally related to the antitumor antibiotic sangivamycin.
1974
1974
The disposition of the antitumor agent, sangivamycin, in mice.
Summary In vivo studies have established that sangivamycin was phosphorylated and incorporated into the nucleic acids of mouse… 
1968
1968
Nucleoside antibiotics. I. Biochemical tools for studying the structural requirements for interaction at the catalytic and regulatory sites of ribonucleotide reductase from Lactobacillus leichmannii.
Abstract The structural requirements for reactivity at the substrate site and for interaction at the regulatory site of…