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sangivamycin

Known as: 4-amino-5-carboxamido-7-(D-ribofuranosyl)-pyrrolo-(2,3-d)pyrimidine 
 
National Institutes of Health

Papers overview

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2008
2008
Pyrrolopyrimidine nucleosides analogs, collectively referred to as deazapurines, are an important class of structurally diverse… Expand
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2008
2008
BackgroundThe nucleoside analog, ARC (NSC 188491) is a recently characterized transcriptional inhibitor that selectively kills… Expand
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2007
2007
BACKGROUND Sangivamycin, an antibiotic with anti-tumor and anti-herpes virus activities by inhibiting both DNA/RNA synthesis and… Expand
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Highly Cited
2003
Highly Cited
2003
We used synthetic lethal high-throughput screening to interrogate 23,550 compounds for their ability to kill engineered… Expand
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Highly Cited
1995
Highly Cited
1995
Sublethal concentrations of reactive oxygen intermediates including H2O2 can alter human T cell function and inhibit… Expand
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1990
1990
We have studied the expression of an immediate/early type gene, Egr-1, in murine B lymphocyte responses to Ag receptor-generated… Expand
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1989
1989
During the screening for the inhibitors of protein kinase C (PKC), we found that a streptomycete produced an inhibitor in our… Expand
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1989
1989
The effects of the protein kinase C inhibitor H-7 on the actin cytoskeleton of cultured cells (Swiss 3T3 and PTK2) are described… Expand
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1988
1988
Protein kinase C functions prominently in cell regulation via its pleiotropic role in signal transduction processes. Certain… Expand
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1987
1987
Seven arabinosyl, 2'-deoxyribosyl, and ribosyl pyrrolo[2,3-d]pyrimidines were evaluated in vitro for activity against human… Expand
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