saikogenin D

National Institutes of Health

Papers overview

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2017

2017

Bupleurum chinense Roots: a Bioactivity-Guided Approach toward Saponin-Type NF-κB Inhibitors.

Xin Liu, Simone Latkolik, +8 authors Rudolf Bauer
Planta medica
2017

The roots of Bupleurum chinense have a long history in traditional medicine to treat infectious diseases and inflammatory… (More)

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2014

2014

A new saikogenin from the roots of Bupleurum bicaule.

Nan Xu, Ya-nan Shi, Xu Zhong, Y. R. Cao, Li Wang, Tian-zhu Jia
Chinese journal of natural medicines
2014

AIM To study the chemical constituents from the roots of Buleurum bicaule Helm (Apiaceae). METHOD Silica gel, Sephadex LH-20… (More)

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2006

2006

Participation of epoxygenase activation in saikogenin D-induced inhibition of prostaglandin E(2) synthesis.

Yasufumi Toriniwa, Xiaochuan Lv, Yasuo Kodama, Yasushi Ohizumi, Makoto A Yoshida, Norimichi Nakahata
The Journal of pharmacy and pharmacology
2006

We examined the effect of saikogenin D on arachidonic acid metabolism in C6 rat glioma cells to clarify its anti-inflammatory… (More)

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2004

2004

Determination of saikosaponin derivatives in Radix bupleuri and in pharmaceuticals of the chinese multiherb remedy xiaochaihu-tang using liquid chromatographic tandem mass spectrometry.

Yuanwu Bao, Chuan Li, Hongwu Shen, Fa-jun Nan
Analytical chemistry
2004

Saikosaponins are bioactive oleanane saponins derived from the Chinese medicinal herb Radix bupleuri ("chaihu" in Chinese). An LC… (More)

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2003

2003

Dual effect of saikogenin D: in vitro inhibition of prostaglandin E2 production and elevation of intracellular free Ca2+ concentration in C6 rat glioma cells.

Yasuo Kodama, Lv Xiaochuan, Chikako Tsuchiya, Yasushi Ohizumi, Makoto A Yoshida, Norimichi Nakahata
Planta medica
2003

To clarify the pharmacological profile of saikogenin D, we examined the effect of saikogenin D on prostaglandin E2 (PGE2… (More)

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1990

1990

Protective effect of saikosaponin A, saikosaponin D and saikogenin D against Pseudomonas aeruginosa infection in mice.

Yoshio Kumazawa, Tetsuya Kawakita, Hirokazu Takimoto, Kazuo Nomoto
International journal of immunopharmacology
1990

Effects of saikosaponins and their genins on nonspecific resistance against Pseudomonas aeruginosa and Listeria monocytogenes… (More)

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1989

1989

Corticosterone secretion-inducing activity of saikosaponin metabolites formed in the alimentary tract.

Motoko Nose, Suguru Amagaya, Yasuyuki Ogihara
Chemical & pharmaceutical bulletin
1989

The corticosterone secretion-inducing activities of saikosaponin a, saikosaponin c and saikosaponin d, isolated from the root of… (More)

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