sacituzumab govitecan

An antibody drug conjugate containing the humanized monoclonal antibody, hRS7, against tumor-associated calcium signal transducer 2 (TACSTD2 or TROP2… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

2010-2017
051020102017

Papers overview

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2017
2017
Purpose Trop-2, expressed in most solid cancers, may be a target for antibody-drug conjugates (ADCs) in non-small-cell lung… (More)
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2017
2017
Purpose Trop-2, expressed in most triple-negative breast cancers (TNBCs), may be a potential target for antibody-drug conjugates… (More)
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Review
2017
Review
2017
INTRODUCTION Despite advances in the diagnosis and treatment of patients with cancer, patients with metastatic cancer have… (More)
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2017
2017
BACKGROUND Sacituzumab govitecan (IMMU-132), an antitrophoblastic cell-surface antigen (anti-Trop-2) humanized antibody-SN-38… (More)
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2017
2017
Purpose: We evaluated a Trop-2-targeting antibody conjugated with SN-38 in metastatic small cell lung cancer (mSCLC) patients… (More)
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2016
2016
Patients with metastatic, platinum-resistant urothelial carcinoma (PRUC) have no Food and Drug Administration-approved therapies… (More)
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2015
2015
PURPOSE This study examined the delivery of SN-38 to Trop-2-expressing tumors and assessed the constitutive products in the serum… (More)
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2015
2015
Sacituzumab govitecan (IMMU-132) is an antibody-drug conjugate (ADC) made from a humanized anti-Trop-2 monoclonal antibody (hRS7… (More)
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2015
2015
Trop-2 is a novel target for ADC therapy because of its high expression by many solid cancers. The rational development of IMMU… (More)
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2015
2015
PURPOSE Sacituzumab govitecan (IMMU-132) is an antibody-drug conjugate (ADC) targeting Trop-2, a surface glycoprotein expressed… (More)
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