rottlerin

 
National Institutes of Health

Papers overview

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2016
2016
BACKGROUND/AIMS The phytochemical polyphenol rottlerin is a potent activator of diverse Ca2+ -sensitive K+ channels. Those… (More)
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Highly Cited
2014
Highly Cited
2014
Autophagy plays an important role in cellular homeostasis through the disposal and recycling of cellular components. Cancer stem… (More)
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Review
2012
Review
2012
Because cancers are caused by deregulation of hundreds of genes, an ideal anticancer agent should target multiple gene products… (More)
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Review
2012
Review
2012
Rottlerin and curcumin are natural plant polyphenols with a long tradition in folk medicine. Over the past two decades, curcumin… (More)
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Review
2007
Review
2007
Rottlerin has been used as a protein kinase Cdelta (PKCdelta)-selective inhibitor in hundreds of studies, on the basis of initial… (More)
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2007
2007
Rottlerin is a pharmacological inhibitor of protein kinase C (PKC) theta, a novel PKC selectively expressed in T lymphocytes. PKC… (More)
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Highly Cited
2007
Highly Cited
2007
The plasma membrane represents an impermeable barrier for most macromolecules. Still some proteins and so-called cell-penetrating… (More)
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Highly Cited
2003
Highly Cited
2003
Interleukin-6 (IL-6) activates cells by binding to the membrane-bound IL-6 receptor (IL-6R) and subsequent formation of a… (More)
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Highly Cited
2000
Highly Cited
2000
The specificities of 28 commercially available compounds reported to be relatively selective inhibitors of particular serine… (More)
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Highly Cited
1994
Highly Cited
1994
Rottlerin, a compound from Mallotus philippinensis, is shown to inhibit protein kinases with some specificity for PKC. To some… (More)
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