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rottlerin

National Institutes of Health

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3 relations

Broader (3)

AcetophenonesBenzopyransEnzyme Inhibitors

Papers overview

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Highly Cited
2008
Highly Cited
2008
PKC-delta/c-Src-mediated EGF receptor transactivation regulates thrombin-induced COX-2 expression and PGE(2) production in rat vascular smooth muscle cells.
Highly Cited
2006
Highly Cited
2006
Coadministration of Sorafenib with Rottlerin Potently Inhibits Cell Proliferation and Migration in Human Malignant Glioma Cells
Mitogen-activated protein kinase (MAPK) and protein kinase C (PKC) are activated in the majority of gliomas and contribute to… 
Highly Cited
2006
Highly Cited
2006
Protein kinase D protects against oxidative stress-induced intestinal epithelial cell injury via Rho/ROK/PKC-δ pathway activation
Protein kinase D (PKD) is a novel protein serine kinase that has recently been implicated in diverse cellular functions… 
Highly Cited
2005
Highly Cited
2005
Activation of ERK during DNA damage-induced apoptosis involves protein kinase Cdelta.
Highly Cited
2004
Highly Cited
2004
Downregulation of Osteoblast Markers and Induction of the Glial Fibrillary Acidic Protein by Oncostatin M in Osteosarcoma Cells Require PKCδ and STAT3
The effects of OSM on proliferation and differentiation of osteosarcoma and nontransformed osteoblasts were analyzed. OSM… 
Highly Cited
2004
Highly Cited
2004
PKC-δ and CaMKII-δ2 mediate ATP-dependent activation of ERK1/2 in vascular smooth muscle
ATP, a purinergic receptor agonist, has been shown to be involved in vascular smooth muscle (VSM) cell DNA synthesis and cell… 
Highly Cited
2004
Highly Cited
2004
Expression of adhesion molecules by sphingosine 1-phosphate and histamine in endothelial cells.
Highly Cited
2002
Highly Cited
2002
A role for PKC-δ and PI 3-kinase in TNF-α-mediated antiapoptotic signaling in the human neutrophil
The proinflammatory cytokine tumor necrosis factor (TNF)-α has been implicated in the attenuation of neutrophil spontaneous… 
Highly Cited
2000
Highly Cited
2000
Novel compounds, '1,3-selenazine derivatives' as specific inhibitors of eukaryotic elongation factor-2 kinase.
Highly Cited
2000
Highly Cited
2000
Interaction between Protein Kinase C δ and the c-Abl Tyrosine Kinase in the Cellular Response to Oxidative Stress*
Protein kinase C (PKC) isoforms are phosphorylated on tyrosine in the response of cells to oxidative stress. The present studies… 
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