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rosuvastatin lactone

National Institutes of Health

Papers overview

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2018
2018
Myotoxicity is a significant factor contributing to the poor adherence and reduced effectiveness in the treatment of statins… Expand
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2017
2017
A microfluidic liver biochip was coupled with a mass spectrometer to detect in real time the drug metabolism of hepatocytes. The… Expand
2016
2016
PurposeRosuvastatin disposition is modulated by the expression and activity of several membrane transporters including BCRP… Expand
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Highly Cited
2014
Highly Cited
2014
PurposeSystemic exposure to rosuvastatin in Asian subjects living in Japan or Singapore is approximately twice that observed in… Expand
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Review
2013
Review
2013
Cardiovascular disorders are the leading cause of death in the United States. Members of 3-hydroxy-3-methylglutaryl-coenzyme A… Expand
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2012
2012
The relaxant effect of the lactone of rosuvastatin was evaluated on aortic rings from male Wistar rats (250-300 g) with and… Expand
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2010
2010
The first entry to statins via lactonized side chain is reported, exemplified by the synthesis of rosuvastatin. The key step is… Expand
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2010
2010
BACKGROUND Cross-study comparisons suggest that systemic exposure (AUC) to rosuvastatin calcium, a 3-hydroxy-3-methylglutaryl… Expand
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2009
2009
Rosuvastatin (RST) and atorvastatin (ATO) are prescription drugs and members in the statin family used for the treatment of… Expand
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