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rosuvastatin lactone

 
National Institutes of Health

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2018
2018
Myotoxicity is a significant factor contributing to the poor adherence and reduced effectiveness in the treatment of statins… Expand
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2017
2017
A microfluidic liver biochip was coupled with a mass spectrometer to detect in real time the drug metabolism of hepatocytes. The… Expand
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2016
2016
PurposeRosuvastatin disposition is modulated by the expression and activity of several membrane transporters including BCRP… Expand
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Highly Cited
2014
Highly Cited
2014
PurposeSystemic exposure to rosuvastatin in Asian subjects living in Japan or Singapore is approximately twice that observed in… Expand
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Review
2013
Review
2013
Cardiovascular disorders are the leading cause of death in the United States. Members of 3-hydroxy-3-methylglutaryl-coenzyme A… Expand
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2012
2012
The relaxant effect of the lactone of rosuvastatin was evaluated on aortic rings from male Wistar rats (250-300 g) with and… Expand
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2010
2010
The first entry to statins via lactonized side chain is reported, exemplified by the synthesis of rosuvastatin. The key step is… Expand
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2010
2010
BACKGROUND Cross-study comparisons suggest that systemic exposure (AUC) to rosuvastatin calcium, a 3-hydroxy-3-methylglutaryl… Expand
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2009
2009
Rosuvastatin (RST) and atorvastatin (ATO) are prescription drugs and members in the statin family used for the treatment of… Expand
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