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ropizine

Known as: 1-benzhydryl-4-(6-methyl-2-pyridylmethyleneimino)piperazine, 1-piperazinamine, 4-(diphenylmethyl)-N-((6-methyl-2-pyridinyl)methylene)- 
 
National Institutes of Health

Papers overview

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Review
2004
Review
2004
Summary1.Dextromethorphan (DM), a dextrorotatory nonopioid antitussive, binds to specific high-affinity sites in the central… Expand
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1998
1998
1. The anticonvulsant potency of a series of structurally-dissimilar compounds which possess nanomolar affinities for high… Expand
1992
1992
Dextromethorphan (DM) binds to high- and low-affinity sites in the rat brain. The high-affinity DM binding is inhibited by… Expand
1990
1990
Computer-assisted analysis of self- and cross-displacement studies between dextromethorphan (DM) and (+)-3-(3-hydroxyphenyl)-N-(1… Expand
1990
1990
Ropizine (10 microM) produces a simultaneous enhancement and inhibition of [3H]dextromethorphan (DM) high-affinity binding to… Expand
Highly Cited
1989
Highly Cited
1989
Equilibrium binding analysis demonstrated that (+)-[3H]3-(3-hydroxyphenyl)-N-(1-propyl)piperidine [(+)-[3H]3-PPP] binds in guinea… Expand
1989
1989
Dextromethorphan (DM) is an antitussive with anticonvulsant activity that binds to high‐ and low‐affinity sites in guinea pig… Expand
Highly Cited
1988
Highly Cited
1988
Dextromethorphan (DM), a non-narcotic antitussive with anticonvulsant activity, binds to high (Kd, 57 nM)- and low-affinity sites… Expand
1979
1979
The anticonvulsant effects of four benzhydryl piperazines, SC-13504 (ropizine, an anticonvulsant), hydroxyzine (HDX, an… Expand
1978
1978
Studies were conducted on a colony of purebred beagle dogs. Animals with spontaneous seizures were classed as epileptic beagles… Expand