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ritrosulfan

Known as: ritosulfan, Lycurim, lykurim 
A sulfonate-based alkylation agent with potential antineoplastic activity. Ritrosulfan appears to alkylate DNA, thereby producing DNA crosslinks… Expand
National Institutes of Health

Papers overview

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2001
2001
This paper deals with results of the search for anticancer agents achieved at IDR during the period of 1953-1983. This research… Expand
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1983
1983
A recently developed metastatic tumor model was used to study the therapeutic response of liver metastases derived from… Expand
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1983
1983
The mutagenicity of various alkylating sugar alcohol derivatives in the Salmonella-microsome assay was studied, and the effects… Expand
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1982
1982
The purpose of this study was to test for a possible synergism in the antitumor action of the antimetabolite pyrazofurin (PF) and… Expand
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1982
1982
Hepatoma 8999 was sensitive to Lycurim [1,4-di-(methylsulfonyloxy-ethylamino)-1,4-dideoxy-ms-erythritol] with a mean lethal dose… Expand
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1981
1981
Lycurim was used in the therapy of 41 CLL patients, in 34 a positive clinical effect was found. The effect was marked in cases of… Expand
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1980
1980
Lycurium [1,4-di-(methylsulfonyloxy-ethylamino)-1,4-didesoxy-erythrioldimethylsulfonate; R-74; NSC-122402] undergoes rapid… Expand
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1978
1978
  • T. Raposa
  • Mutation research
  • 1978
  • Corpus ID: 24280752
The effect of various cytostatic drugs was studied on the frequency of sister chromatid exchanges (SCEs) in vitro and in PHA… Expand
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1978
1978
Abstract Tumour-age dependent activity of an antimetabolite and some alkylating agents was studied using a newly described in… Expand
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1976
1976
The Colcemid-resistant L--53 cell strain was examined for cross-resistance to metaphase inhibotors (Vincristine, Vinblastine… Expand
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