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Sigma1 receptors (σ1Rs) represent a structurally unique class of intracellular proteins that function as chaperones. σ1Rs… Expand Berberine, an alkaloid isolated from Berberis aristata Linn. has been used in the Indian system of medicines as a stomachic… Expand Rimcazole is a carbazole derivative that acts in part as a sigma receptor antagonist. Wellcome Research Laboratories introduced… Expand Several sigma receptor ligands have been reported to also have affinity for the dopamine transporter, among them rimcazole (9-[3… Expand In an attempt to discover a cocaine‐abuse pharmacotherapeutic, extensive investigation has been directed toward elucidating the… Expand The authors examined the affinities of 36 typical and atypical antipsychotic agents for the cloned rat 5-hydroxytryptamine-6 (5… Expand The regulation of the central σr‐binding site was investigated using both in vitro and in vivo manipulations in conjunction with… Expand Extracellular single unit recording techniques were used to study the effects of selective sigma-receptor agonist [(+)-3-PPP… Expand This study evaluated with electrophysiological and behavioral techniques the ability of rimcazole, a novel putative antipsychotic… Expand Rimcazole (BW 234U) is a potential antipsychotic agent which in open-clinical trials appears to be effective in acute… Expand