rifapentine

Known as: 3-(((4-Cyclopentyl-1-piperazinyl)imino)methyl)rifamycin, rifapentine [Chemical/Ingredient], 3-(((4-cyclopentyl-1-piperazinyl)imino)methyl)rifamycin SV 
A long-acting, cyclopentyl-substituted derivative of rifamycin used to treat mycobacterium infections.
National Institutes of Health

Papers overview

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Highly Cited
2014
Highly Cited
2014
BACKGROUND Tuberculosis regimens that are shorter and simpler than the current 6-month daily regimen are needed. METHODS We… (More)
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Highly Cited
2011
Highly Cited
2011
BACKGROUND Treatment of latent Mycobacterium tuberculosis infection is an essential component of tuberculosis control and… (More)
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2009
2009
RATIONALE Regimens recommended to treat latent tuberculosis infection (LTBI) are 3 to 9 months long. A 2-month rifampin… (More)
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Highly Cited
2007
Highly Cited
2007
BACKGROUND Availability of an ultra-short-course drug regimen capable of curing patients with tuberculosis in 2 to 3 mo would… (More)
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Highly Cited
2006
Highly Cited
2006
RATIONALE Treatment of latent tuberculosis (TB) infection with weekly rifapentine and isoniazid is a potentially effective… (More)
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2005
2005
RATIONALE Comparison of the early bactericidal activity (EBA) of rifapentine and its pharmacokinetics with those of rifampin to… (More)
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2005
2005
RATIONALE Treatment of tuberculosis with an efficacious once-weekly regimen would be a significant achievement in improving… (More)
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Highly Cited
2003
Highly Cited
2003
To understand why once-weekly isoniazid/rifapentine therapy for tuberculosis was less effective than twice-weekly isoniazid… (More)
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Highly Cited
2002
Highly Cited
2002
BACKGROUND Rifapentine has a long half-life in serum, which suggests a possible treatment once a week for tuberculosis. We aimed… (More)
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1997
1997
In our laboratory, primary human hepatocytes are being investigated as an in vitro experimental system for the evaluation of… (More)
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