ribosomal protein S6 kinase, 70kD, polypeptide 2

Known as: Ribosomal Protein S6 Kinase, 70kDa, Polypeptide 2, p70S6KB, Serine/Threonine-Protein Kinase 14 B 
Ribosomal protein S6 kinase beta-2 (482 aa, ~53 kDa) is encoded by the human RPS6KB2 gene. This protein is involved in serine/threonine protein… (More)
National Institutes of Health

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Highly Cited
2009
Highly Cited
2009
Caloric restriction (CR) protects against aging and disease, but the mechanisms by which this affects mammalian life span are… (More)
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Highly Cited
2009
Highly Cited
2009
mTOR (mammalian target of rapamycin) stimulates cell growth by phosphorylating and promoting activation of AGC (protein kinase A… (More)
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Highly Cited
2007
Highly Cited
2007
Converging signals from the mammalian target of rapamycin (mTOR) and phosphoinositide 3-kinase (PI3K) pathways are well… (More)
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Review
2006
Review
2006
Recent studies are beginning to disclose a signaling network involved in regulating cell size. Although many links and effectors… (More)
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Highly Cited
2004
Highly Cited
2004
Tuberous sclerosis complex (TSC) is a genetic disorder caused by mutations in either of the two tumor suppressor genes TSC1 or… (More)
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Highly Cited
2004
Highly Cited
2004
Activation of 40S ribosomal protein S6 kinases (S6Ks) is mediated by anabolic signals triggered by hormones, growth factors, and… (More)
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Highly Cited
2003
Highly Cited
2003
Mammalian target of rapamycin (mTOR) is a key regulator of cell growth acting via two independent targets, ribosomal protein S6… (More)
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Highly Cited
2003
Highly Cited
2003
BACKGROUND Cardiac hypertrophy, or an increase in heart size, is an important risk factor for cardiac morbidity and mortality… (More)
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Highly Cited
2002
Highly Cited
2002
Tuberous sclerosis complex (TSC) is an autosomal dominant genetic disorder that occurs upon mutation of either the TSC1 or TSC2… (More)
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Highly Cited
1998
Highly Cited
1998
Recent studies have shown that the p70(s6k)/p85(s6k) signaling pathway plays a critical role in cell growth by modulating the… (More)
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