FAQ

rho Guanine Nucleotide Dissociation Inhibitor beta

Known as: rho GDP-Dissociation Inhibitor beta, rho GDP-Dissociation Inhibitor 2, rhoGDIbeta 
A rho GDP-dissociation inhibitor subtype that is highly expressed in hematopoietic cells and in LYMPHOCYTES. The expression of this subtype is… (More)
National Institutes of Health

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Topic mentions per year

1971-2017
05101519712017

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10 relations
ARHGDIB geneIn BloodProcess of secretionagonists
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ARHGDIB protein, human

Related mentions per year

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1936-2018
19401960198020002020
rho Guanine Nucleotide Dissociation Inhibitor beta
physiological aspects
In Blood
chemical synthesis
standards characteristics
Process of secretion

Papers overview

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2012
2012
RhoGDI2 suppresses lung metastasis in mice by reducing tumor versican expression and macrophage infiltration.
Half of patients with muscle-invasive bladder cancer develop metastatic disease, and this is responsible for most of the deaths… (More)
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Highly Cited
2011
Highly Cited
2011
Rac1 GTPase in rodent kidneys is essential for salt-sensitive hypertension via a mineralocorticoid receptor-dependent pathway.
Hypertension is a leading contributor to cardiovascular mortality worldwide. Despite this, its underlying mechanism(s) and the… (More)
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2009
2009
RhoGDI2 expression is associated with tumor growth and malignant progression of gastric cancer.
PURPOSE Rho GDP dissociation inhibitor 2 (RhoGDI2) has been identified as a regulator of Rho family GTPase. However, there is… (More)
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2009
2009
Rho GDP dissociation inhibitor 2 suppresses metastasis via unconventional regulation of RhoGTPases.
Rho GDP dissociation inhibitor 2 (RhoGDI2) has been identified as a metastasis suppressor in bladder and possibly other cancers… (More)
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2009
2009
Src phosphorylation of RhoGDI2 regulates its metastasis suppressor function.
RhoGDI2 is a suppressor of metastasis in human bladder cancer. Although diminished RhoGDI2 expression in tumors is associated… (More)
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2007
2007
Neuromedin U is regulated by the metastasis suppressor RhoGDI2 and is a novel promoter of tumor formation, lung metastasis and cancer cachexia
Most deaths from urinary bladder cancer are owing to metastatic disease. A reduction in Rho GDP Dissociation Inhibitor 2 (RhoGDI2… (More)
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Highly Cited
2005
Highly Cited
2005
Endothelin axis is a target of the lung metastasis suppressor gene RhoGDI2.
Half of patients treated for locally advanced bladder cancer relapse with often fatal metastatic disease to the lung. We have… (More)
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Highly Cited
2004
Highly Cited
2004
Reduced expression of metastasis suppressor RhoGDI2 is associated with decreased survival for patients with bladder cancer.
PURPOSE RhoGDI2 was recently shown to be a metastasis suppressor gene in models of bladder cancer. We sought to further… (More)
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Highly Cited
2002
Highly Cited
2002
RhoGDI2 is an invasion and metastasis suppressor gene in human cancer.
To discover novel metastasis suppressor genes that are clinically relevant in common human cancers, we used isogenic human… (More)
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1997
1997
RhoGDIgamma: a GDP-dissociation inhibitor for Rho proteins with preferential expression in brain and pancreas.
GDP-dissociation inhibitors (GDIs) play a primary role in modulating the activation of GTPases and may also be critical for the… (More)
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