rho-Associated Kinases

Known as: Coiled-Coil Kinase, rho-Associated, rho-Associated Kinase, rho Kinase 
A group of intracellular-signaling serine threonine kinases that bind to RHO GTP-BINDING PROTEINS. They were originally found to mediate the effects… (More)
National Institutes of Health

Papers overview

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Review
2008
Review
2008
Rho GTPases are key regulators of cytoskeletal dynamics and affect many cellular processes, including cell polarity, migration… (More)
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Highly Cited
2003
Highly Cited
2003
The neurotrophin receptor p75NTR is involved in the regulation of axonal elongation by neurotrophins as well as several myelin… (More)
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Highly Cited
2002
Highly Cited
2002
BACKGROUND Hypoxia-induced pulmonary hypertension is a major cause of morbidity and mortality. Hypoxia induces pulmonary… (More)
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Highly Cited
2000
Highly Cited
2000
Endothelial cells (ECs) actively regulate the extravasation of blood constituents. On stimulation by vasoactive agents and… (More)
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Highly Cited
1999
Highly Cited
1999
Rho-associated kinase (Rho-kinase), which is activated by the small GTPase Rho, phosphorylates myosin-binding subunit (MBS) of… (More)
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Highly Cited
1999
Highly Cited
1999
Rho-associated kinase (Rho-kinase) from chicken gizzard smooth muscle was purified to apparent homogeneity (160 kDa on SDS… (More)
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Highly Cited
1998
Highly Cited
1998
A critical role for the small GTPase Rho and one of its targets, p160ROCK (a Rho-associated coiled coil-forming protein kinase… (More)
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Highly Cited
1997
Highly Cited
1997
Small GTPase Rho plays pivotal roles in the Ca2+ sensitization of smooth muscle. However, the GTP-bound active form of Rho failed… (More)
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Highly Cited
1996
Highly Cited
1996
The small guanosine triphosphatase Rho is implicated in myosin light chain (MLC) phosphorylation, which results in contraction of… (More)
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Highly Cited
1996
Highly Cited
1996
The small GTPase Rho is implicated in physiological functions associated with actin-myosin filaments such as cytokinesis, cell… (More)
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