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rho-Associated Kinases

Known as: Coiled-Coil Kinase, rho-Associated, rho-Associated Kinase, rho Kinase 
A group of intracellular-signaling serine threonine kinases that bind to RHO GTP-BINDING PROTEINS. They were originally found to mediate the effects… Expand
National Institutes of Health

Papers overview

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Review
2018
Review
2018
In an elegant example of bench-to-bedside research, a hypothesis that cells in the outflow pathway actively regulate conventional… Expand
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Review
2011
Review
2011
The human intestinal epithelium is formed by a single layer of epithelial cells that separates the intestinal lumen from the… Expand
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Review
2008
Review
2008
Rho GTPases are key regulators of cytoskeletal dynamics and affect many cellular processes, including cell polarity, migration… Expand
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Review
2002
Review
2002
During the past 20 years, it has become generally accepted that the modulation of fibroblastic cells towards the myofibroblastic… Expand
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Highly Cited
2001
Highly Cited
2001
PURPOSE The goal of this study was to investigate the role of Rho kinase in the modulation of aqueous humor outflow facility. Rho… Expand
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Highly Cited
1999
Highly Cited
1999
Rho-associated kinase (Rho-kinase), which is activated by the small GTPase Rho, phosphorylates myosin-binding subunit (MBS) of… Expand
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Highly Cited
1998
Highly Cited
1998
A critical role for the small GTPase Rho and one of its targets, p160ROCK (a Rho-associated coiled coil-forming protein kinase… Expand
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Highly Cited
1997
Highly Cited
1997
Small GTPase Rho plays pivotal roles in the Ca2+ sensitization of smooth muscle. However, the GTP-bound active form of Rho failed… Expand
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Highly Cited
1996
Highly Cited
1996
The small guanosine triphosphatase Rho is implicated in myosin light chain (MLC) phosphorylation, which results in contraction of… Expand
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Highly Cited
1996
Highly Cited
1996
The small GTPase Rho is implicated in physiological functions associated with actin-myosin filaments such as cytokinesis, cell… Expand
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