retroviral strand transfer activity

ABSTRACT Reverse transcriptase (RT) and integrase (IN) are two key catalytic enzymes encoded by all retroviruses. It has been… Expand

Styrylquinoline derivatives (SQ) efficiently inhibit the 3'-processing activity of integrase (IN) with IC50 values of between 0.5… Expand

The process of integrating the reverse-transcribed HIV-1 DNA into the host chromosomal DNA is catalyzed by the virally encoded… Expand

Human immunodeficiency virus (HIV) nucleocapsid protein (NC) influences HIV reverse transcriptase (RT) catalyzed strand transfer… Expand

The integrase protein of human immunodeficiency virus type 1 is necessary for the stable integration of the viral genome into… Expand

Two DNA strand transfers are required during reverse transcription of the RNA genome of retroviruses to complete provirus… Expand

Replication of the hepadnavirus genome occurs by reverse transcription of an RNA pregenome and is mediated by the viral… Expand

Retroviral DNA integration involves a coordinated set of DNA cutting and joining reactions. Linear viral DNA is cleaved at each 3… Expand

The Mu in vitro strand transfer reaction proceeds via two stable higher order nucleoprotein complexes, the Type 1 and Type 2… Expand

The Escherichia coli recQ gene, a member of the RecF recombination gene family, was set in an overexpression plasmid, and its… Expand