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retroviral strand transfer activity

Known as: strand transfer reaction 
Catalysis of the covalent insertion of processed 3'-viral DNA ends into host chromosomal DNA by a trans-esterification reaction. [PMID:22580823]
National Institutes of Health

Papers overview

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Highly Cited
2004
Highly Cited
2004
Interaction between Human Immunodeficiency Virus Type 1 Reverse Transcriptase and Integrase Proteins
ABSTRACT Reverse transcriptase (RT) and integrase (IN) are two key catalytic enzymes encoded by all retroviruses. It has been… 
Highly Cited
2004
Highly Cited
2004
Mechanism of HIV-1 integrase inhibition by styrylquinoline derivatives in vitro.
Styrylquinoline derivatives (SQ) efficiently inhibit the 3'-processing activity of integrase (IN) with IC50 values of between 0.5… 
Highly Cited
2002
Highly Cited
2002
Diketo acid inhibitor mechanism and HIV-1 integrase: Implications for metal binding in the active site of phosphotransferase enzymes
The process of integrating the reverse-transcribed HIV-1 DNA into the host chromosomal DNA is catalyzed by the virally encoded… 
Highly Cited
1996
Highly Cited
1996
(-)-Arctigenin as a lead structure for inhibitors of human immunodeficiency virus type-1 integrase.
The natural dibenzylbutyrolactone type lignanolide (-)-arctigenin (2), an inhibitor of human immunodeficiency virus type-1 (HIV-1… 
Highly Cited
1995
Highly Cited
1995
Influence of Human Immunodeficiency Virus Nucleocapsid Protein on Synthesis and Strand Transfer by the Reverse Transcriptase in Vitro(*)
Human immunodeficiency virus (HIV) nucleocapsid protein (NC) influences HIV reverse transcriptase (RT) catalyzed strand transfer… 
Highly Cited
1994
Highly Cited
1994
Hepadnavirus reverse transcription initiates within the stem-loop of the RNA packaging signal and employs a novel strand transfer
Replication of the hepadnavirus genome occurs by reverse transcription of an RNA pregenome and is mediated by the viral… 
Highly Cited
1991
Highly Cited
1991
HIV-1 DNA integration: Mechanism of viral DNA cleavage and DNA strand transfer
Highly Cited
1991
Highly Cited
1991
Structural aspects of a higher order nucleoprotein complex: induction of an altered DNA structure at the Mu‐host junction of the Mu type 1 transpososome.
The Mu in vitro strand transfer reaction proceeds via two stable higher order nucleoprotein complexes, the Type 1 and Type 2… 
Highly Cited
1990
Highly Cited
1990
Escherichia coli RecQ protein is a DNA helicase.
The Escherichia coli recQ gene, a member of the RecF recombination gene family, was set in an overexpression plasmid, and its… 
Highly Cited
1987
Highly Cited
1987
Transpososomes: Stable protein-DNA complexes involved in the in vitro transposition of bacteriophage Mu DNA
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