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retinoid isomerohydrolase

Known as: retinoid isomerase, retinol isomerase 
 
National Institutes of Health

Topic mentions per year

Topic mentions per year

1989-2018
01219892018

Related topics

Related topics

3 relations
RPE65 gene

Narrower (1)

RPE65c protein, zebrafish

Broader (1)

cis-trans-Isomerases

Related mentions per year

Related mentions per year

1988-2018
19801990200020102020
retinoid isomerohydrolase
cis-trans-Isomerases
RPE65 gene
RPE65c protein, zebrafish

Papers overview

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2018
2018
Retinoid isomerase inhibitors impair but do not block mammalian cone photoreceptor function.
Visual function in vertebrates critically depends on the continuous regeneration of visual pigments in rod and cone… (More)
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2014
2014
Pathophysilogical mechanism and treatment strategies for Leber congenital amaurosis.
Mutations in retinoid isomerase, RPE65, or lecithin-retinol acyltransferase (LRAT) disrupt 11-cis-retinal recycling and cause… (More)
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2013
2013
Identification of DES1 as a Vitamin A Isomerase in Müller Glial Cells of the Retina
Absorption of a light particle by an opsin-pigment causes photoisomerization of its retinaldehyde chromophore. Restoration of… (More)
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2012
2012
Chemical chaperone TUDCA preserves cone photoreceptors in a mouse model of Leber congenital amaurosis.
PURPOSE Mutations in either retinoid isomerase (RPE65) or lecithin-retinol acyltransferase (LRAT) lead to Leber congenital… (More)
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2010
2010
RPE65, visual cycle retinol isomerase, is not inherently 11-cis-specific: support for a carbocation mechanism of retinol isomerization.
The mechanism of retinol isomerization in the vertebrate retina visual cycle remains controversial. Does the isomerase enzyme… (More)
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2009
2009
Crystal structure of native RPE65, the retinoid isomerase of the visual cycle.
Vertebrate vision is maintained by the retinoid (visual) cycle, a complex enzymatic pathway that operates in the retina to… (More)
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Review
2009
Review
2009
Why the Inverted Human Retina Is a Superior Design
It is often claimed that the human retina is poorly designed because light must travel through the nerves and blood vessels to… (More)
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2005
2005
Chicken retinas contain a retinoid isomerase activity that catalyzes the direct conversion of all-trans-retinol to 11-cis-retinol.
Vertebrate retinas contain two types of light-detecting cells. Rods subserve vision in dim light, while cones provide color… (More)
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1989
1989
Solubilization and partial purification of retinyl ester synthetase and retinoid isomerase from bovine ocular pigment epithelium.
Studies reported previously from this laboratory have demonstrated that membranes from the pigment epithelium of the vertebrate… (More)
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1989
1989
Distribution of retinol isomerase in vertebrate eyes and its emergence during retinal development.
Ocular tissue homogenates were incubated in darkness with [11,12-3H] all-trans retinol. Formation of radiolabeled 11-cis retinol… (More)
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