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retinoid isomerohydrolase

Known as: retinoid isomerase, retinol isomerase 
 
National Institutes of Health

Papers overview

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Review
2016
Review
2016
Recent progress in molecular understanding of the retinoid cycle in mammalian retina stems from painstaking biochemical… Expand
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2012
2012
PURPOSE Mutations in either retinoid isomerase (RPE65) or lecithin-retinol acyltransferase (LRAT) lead to Leber congenital… Expand
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Highly Cited
2009
Highly Cited
2009
Inactivating mutations in the retinoid isomerase (RPE65) or lecithin:retinol acyltransferase (LRAT) genes cause Leber congenital… Expand
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2009
2009
RPE65 is a retinoid isomerase required for the production of 11-cis-retinal, the chromophore of both cone and rod visual pigments… Expand
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2009
2009
In animals, visual pigments are essential for photoreceptor function and survival. These G-protein-coupled receptors consist of a… Expand
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Highly Cited
2008
Highly Cited
2008
In animals, successful production of the visual chromophore (11-cis-retinal or derivatives thereof such as 11-cis-3-hydroxy… Expand
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2008
2008
PURPOSE To define rod and cone function further in terms of visual cycle mechanism, the retinal phenotype resulting from Rpe65… Expand
Highly Cited
2005
Highly Cited
2005
Vertebrate retinas contain two types of light-detecting cells. Rods subserve vision in dim light, while cones provide color… Expand
Highly Cited
1990
Highly Cited
1990
Upon absorption of a photon, the 11-cis retinaldehyde chromophore of rhodopsin is isomerized and reduced to all-trans retinol… Expand
Highly Cited
1989
Highly Cited
1989
Studies reported previously from this laboratory have demonstrated that membranes from the pigment epithelium of the vertebrate… Expand