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retinoid isomerohydrolase
Known as:
retinoid isomerase
, retinol isomerase
National Institutes of Health
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Related topics
Related topics
2 relations
RPE65 gene
Broader (1)
cis-trans-Isomerases
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Review
2016
Review
2016
Retinoids and Retinal Diseases.
P. Kiser
,
K. Palczewski
Annual Review of Vision Science
2016
Corpus ID: 32958252
Recent progress in molecular understanding of the retinoid cycle in mammalian retina stems from painstaking biochemical…
Expand
2014
2014
Chemistry and biology of the initial steps in vision: the Friedenwald lecture.
K. Palczewski
Investigative Ophthalmology and Visual Science
2014
Corpus ID: 1438637
Visual transduction is the process in the eye whereby absorption of light in the retina is translated into electrical signals…
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Highly Cited
2012
Highly Cited
2012
Chemical chaperone TUDCA preserves cone photoreceptors in a mouse model of Leber congenital amaurosis.
Tao Zhang
,
W. Baehr
,
Yingbin Fu
Investigative Ophthalmology and Visual Science
2012
Corpus ID: 35025463
PURPOSE Mutations in either retinoid isomerase (RPE65) or lecithin-retinol acyltransferase (LRAT) lead to Leber congenital…
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Highly Cited
2009
Highly Cited
2009
Loss of cone photoreceptors caused by chromophore depletion is partially prevented by the artificial chromophore pro-drug, 9-cis-retinyl acetate.
T. Maeda
,
A. V. Cideciyan
,
+4 authors
K. Palczewski
Human Molecular Genetics
2009
Corpus ID: 17801925
Inactivating mutations in the retinoid isomerase (RPE65) or lecithin:retinol acyltransferase (LRAT) genes cause Leber congenital…
Expand
2009
2009
In conditions of limited chromophore supply rods entrap 11-cis-retinal leading to loss of cone function and cell death.
M. Samardzija
,
N. Tanimoto
,
+10 authors
C. Grimm
Human Molecular Genetics
2009
Corpus ID: 15161594
RPE65 is a retinoid isomerase required for the production of 11-cis-retinal, the chromophore of both cone and rod visual pigments…
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Highly Cited
2008
Highly Cited
2008
NinaB combines carotenoid oxygenase and retinoid isomerase activity in a single polypeptide
V. Oberhauser
,
Olaf Voolstra
,
A. Bangert
,
J. von Lintig
,
K. Vogt
Proceedings of the National Academy of Sciences
2008
Corpus ID: 23303530
In animals, successful production of the visual chromophore (11-cis-retinal or derivatives thereof such as 11-cis-3-hydroxy…
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2008
2008
Nrl-knockout mice deficient in Rpe65 fail to synthesize 11-cis retinal and cone outer segments.
Kecia L. Feathers
,
A. Lyubarsky
,
+5 authors
Debra Thompson
Investigative Ophthalmology and Visual Science
2008
Corpus ID: 1402575
PURPOSE To define rod and cone function further in terms of visual cycle mechanism, the retinal phenotype resulting from Rpe65…
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Highly Cited
2005
Highly Cited
2005
Chicken retinas contain a retinoid isomerase activity that catalyzes the direct conversion of all-trans-retinol to 11-cis-retinol.
N. Mata
,
A. Ruiz
,
R. Radu
,
T. V. Bui
,
G. Travis
Biochemistry
2005
Corpus ID: 36671968
Vertebrate retinas contain two types of light-detecting cells. Rods subserve vision in dim light, while cones provide color…
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Highly Cited
1990
Highly Cited
1990
Uptake, processing and release of retinoids by cultured human retinal pigment epithelium.
J. Flannery
,
W. O'day
,
B. Pfeffer
,
J. Horwitz
,
D. Bok
Experimental Eye Research
1990
Corpus ID: 26036554
Highly Cited
1989
Highly Cited
1989
Solubilization and partial purification of retinyl ester synthetase and retinoid isomerase from bovine ocular pigment epithelium.
R. Barry
,
F. Cañada
,
R. Rando
Journal of Biological Chemistry
1989
Corpus ID: 9842220
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