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retinoic acid metabolism

Known as: retinoic acid metabolic process, vitamin A1 acid metabolic process, vitamin A1 acid metabolism 
The chemical reactions and pathways involving retinoic acid, one of the three components that makes up vitamin A. [GOC:jl, http://www.indstate.edu… Expand
National Institutes of Health

Related topics

Related topics

3 relations
Retinol Metabolism Pathwayretinal metabolism

Broader (1)

vitamin A metabolism

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2011
Review
2011
Cytochrome P450s in the regulation of cellular retinoic acid metabolism.
The active metabolite of vitamin A, retinoic acid (RA), is a powerful regulator of gene transcription. RA is also a therapeutic… Expand
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Review
2002
Review
2002
Multiple hits during early embryonic development: digenic diseases and holoprosencephaly.
Multiple genetic and environmental factors likely play a role in the phenotypic expression of many Mendelian disorders… Expand
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2001
2001
Ethanol enhances retinoic acid metabolism into polar metabolites in rat liver via induction of cytochrome P4502E1.
BACKGROUND & AIMS Long-term and excessive ethanol intake results in decreased plasma and hepatic levels of retinoic acid (RA… Expand
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Highly Cited
2000
Highly Cited
2000
Cytochrome P450RAI(CYP26) promoter: a distinct composite retinoic acid response element underlies the complex regulation of retinoic acid metabolism.
The catabolism of retinoic acid (RA) is an essential mechanism for restricting the exposure of specific tissues and cells to RA… Expand
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2000
2000
Regulation of CYP26 (cytochrome P450RAI) mRNA expression and retinoic acid metabolism by retinoids and dietary vitamin A in liver of mice and rats.
Retinoic acid (RA), through nuclear retinoid receptors, regulates the expression of numerous genes. However, little is known of… Expand
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Highly Cited
1998
Highly Cited
1998
Mouse P450RAI (CYP26) expression and retinoic acid-inducible retinoic acid metabolism in F9 cells are regulated by retinoic acid receptor gamma and retinoid X receptor alpha.
We have cloned a mouse cDNA homolog of P450RAI, a cytochrome P450 belonging to a new family (CYP26), which has previously been… Expand
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Highly Cited
1997
Highly Cited
1997
Aryl hydrocarbon receptor knockout mice (AHR-/-) exhibit liver retinoid accumulation and reduced retinoic acid metabolism.
Livers from aryl hydrocarbon receptor-null mice showed a 3-fold increase in retinoids and a 65% decrease in retinoic acid… Expand
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1997
1997
Autoinduction of retinoic acid metabolism to polar derivatives with decreased biological activity in retinoic acid-sensitive, but not in retinoic acid-resistant human breast cancer cells.
Previous studies have shown that all-trans-retinoic acid (RA) inhibits in vitro proliferation of hormone-dependent human breast… Expand
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Highly Cited
1995
Highly Cited
1995
Targeted disruption of retinoic acid receptor alpha (RAR alpha) and RAR gamma results in receptor-specific alterations in retinoic acid-mediated differentiation and retinoic acid metabolism.
F9 embryonic teratocarcinoma stem cells differentiate into an epithelial cell type called extraembryonic endoderm when treated… Expand
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Highly Cited
1991
Highly Cited
1991
Expression of cellular retinoic acid binding protein (CRABP) in Escherichia coli. Characterization and evidence that holo-CRABP is a substrate in retinoic acid metabolism.
Cellular retinoic acid binding protein (CRABP) has been expressed efficiently in Escherichia coli from the cDNA of bovine adrenal… Expand
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