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retinoic acid metabolism

Known as: retinoic acid metabolic process, vitamin A1 acid metabolic process, vitamin A1 acid metabolism 
The chemical reactions and pathways involving retinoic acid, one of the three components that makes up vitamin A. [GOC:jl, http://www.indstate.edu… Expand
National Institutes of Health

Related topics

Related topics

3 relations
Retinol Metabolism Pathwayretinal metabolism

Broader (1)

vitamin A metabolism

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2011
Review
2011
Cytochrome P450s in the regulation of cellular retinoic acid metabolism.
The active metabolite of vitamin A, retinoic acid (RA), is a powerful regulator of gene transcription. RA is also a therapeutic… Expand
Highly Cited
2001
Highly Cited
2001
Ethanol enhances retinoic acid metabolism into polar metabolites in rat liver via induction of cytochrome P4502E1.
BACKGROUND & AIMS Long-term and excessive ethanol intake results in decreased plasma and hepatic levels of retinoic acid (RA… Expand
Highly Cited
2000
Highly Cited
2000
Cytochrome P450RAI(CYP26) promoter: a distinct composite retinoic acid response element underlies the complex regulation of retinoic acid metabolism.
The catabolism of retinoic acid (RA) is an essential mechanism for restricting the exposure of specific tissues and cells to RA… Expand
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Review
1998
Review
1998
The emerging role of retinoids and retinoic acid metabolism blocking agents in the treatment of cancer
Although significant advances have been made in the treatment of some malignancies, the prognosis of patients with metastatic… Expand
Highly Cited
1998
Highly Cited
1998
Mouse P450RAI (CYP26) Expression and Retinoic Acid-inducible Retinoic Acid Metabolism in F9 Cells Are Regulated by Retinoic Acid Receptor γ and Retinoid X Receptor α*
We have cloned a mouse cDNA homolog of P450RAI, a cytochrome P450 belonging to a new family (CYP26), which has previously been… Expand
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Highly Cited
1997
Highly Cited
1997
Aryl hydrocarbon receptor knockout mice (AHR-/-) exhibit liver retinoid accumulation and reduced retinoic acid metabolism.
Livers from aryl hydrocarbon receptor-null mice showed a 3-fold increase in retinoids and a 65% decrease in retinoic acid… Expand
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Highly Cited
1995
Highly Cited
1995
Targeted disruption of retinoic acid receptor alpha (RAR alpha) and RAR gamma results in receptor-specific alterations in retinoic acid-mediated differentiation and retinoic acid metabolism.
F9 embryonic teratocarcinoma stem cells differentiate into an epithelial cell type called extraembryonic endoderm when treated… Expand
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Highly Cited
1994
Highly Cited
1994
Microsomal retinoic acid metabolism. Effects of cellular retinoic acid-binding protein (type I) and C18-hydroxylation as an initial step.
This report extends our observation that cellular retinoic acid-binding protein type I (CRABP) serves as substrate for retinoic… Expand
Highly Cited
1991
Highly Cited
1991
Expression of cellular retinoic acid binding protein (CRABP) in Escherichia coli. Characterization and evidence that holo-CRABP is a substrate in retinoic acid metabolism.
Cellular retinoic acid binding protein (CRABP) has been expressed efficiently in Escherichia coli from the cDNA of bovine adrenal… Expand
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Highly Cited
1967
Highly Cited
1967
Pathways of retinol and retinoic acid metabolism in the rat.
1. The metabolism of retinoic acid and retinyl acetate labelled with (14)C in various positions was studied after intravenous… Expand
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