response to simvastatin

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1997-2017
01219972017

Papers overview

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2014
2014
BACKGROUND The importance of functional properties of high-density lipoproteins (HDL) for atheroprotection is increasingly… (More)
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2013
2013
Although statins are known to inhibit proliferation and induce death in a number of cancer cell types, the mechanisms through… (More)
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2012
2012
UNLABELLED Statins are widely prescribed for reducing LDL-cholesterol (C) and risk for cardiovascular disease (CVD), but there is… (More)
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2011
2011
Although statins are widely prescribed medications, there remains considerable variability in therapeutic response. Genetics can… (More)
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Highly Cited
2008
Highly Cited
2008
BACKGROUND HMGCR(3-Hydroxy-3-methylglutaryl coenzyme A reductase), the direct target of statin inhibition, undergoes alternative… (More)
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Highly Cited
2008
Highly Cited
2008
BACKGROUND Use of 3-hydroxyl-3-methylglutaryl-3 coenzyme A reductase (HMGCR) inhibitors, or statins, reduces cardiovascular… (More)
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2002
2002
Response to Simvastatin Therapy in Scandinavian Simvastatin Survival Study (4S) To the Editor: Ballantyne et al1 compared the… (More)
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2000
2000
Simvastatin is an inhibitor of HMG-CoA reductase used in the treatment of hypercholesterolemia. In the present study simvastatin… (More)
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Review
1999
Review
1999
AIMS To investigate whether an interaction between diltiazem and the 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase… (More)
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1997
1997
The aim of this study was to investigate the safety and long-term effects on serum lipid levels of low-dose simvastatin, an… (More)
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