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response to hydroxyurea

Known as: response to HU 
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene… Expand
National Institutes of Health

Papers overview

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2019
2019
Hydroxyurea is FDA-approved and now increasingly used for children with sickle cell anemia (SCA), but dosing strategies… Expand
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2016
2016
β-Thalassemia is the most common hereditary disorder characterized by reduced production of β-globin chains of hemoglobin A (HbA… Expand
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2015
2015
Introduction: Thalassemias are a group of haematological disorders due to quantitative defect of globin chain. Patients require… Expand
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2014
2014
Hydroxyurea has proven efficacy in children and adults with sickle cell anemia (SCA), but with considerable inter-individual… Expand
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2014
2014
Anaplastic meningiomas are rare and aggressive tumors with a high propensity for local recurrence. Surgical resection and… Expand
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2012
2012
Abstract 241 Although they ostensibly have a monogenetic disease, individuals with sickle cell anemia exhibit wide variability in… Expand
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2012
2012
Genotoxic stress caused by a variety of chemical and physical agents may lead to DNA breaks and genome instability. Response to… Expand
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2008
2008
Fetal hemoglobin (HbF) is the major genetic modulator of sickle cell anemia. Candidate gene-based and genome-wide association… Expand
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2004
2004
Hydroxyurea (HU) is an effective treatment for most patients with symptomatic sickle cell anemia, yet the fetal hemoglobin (HbF… Expand
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Highly Cited
1997
Highly Cited
1997
Hydroxyurea (HU) can increase fetal hemoglobin (HbF) in sickle cell anemia (HbSS). To identify determinants of the HbF response… Expand
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