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response to hydroxyurea

Known as: response to HU 
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene… Expand
National Institutes of Health

Papers overview

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2019
2019
Robust clinical and laboratory response to hydroxyurea using pharmacokinetically guided dosing for young children with sickle cell anemia.
Hydroxyurea is FDA-approved and now increasingly used for children with sickle cell anemia (SCA), but dosing strategies… Expand
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2016
2016
Serum Paraoxonase Activity and Malondialdehyde Serum Concentrations Remain Unaffected in Response to Hydroxyurea Therapy in β-Thalassemia Patients.
β-Thalassemia is the most common hereditary disorder characterized by reduced production of β-globin chains of hemoglobin A (HbA… Expand
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2015
2015
Treatment Response to Hydroxyurea in Beta Thalassemia
Introduction: Thalassemias are a group of haematological disorders due to quantitative defect of globin chain. Patients require… Expand
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2014
2014
Whole Exome Sequencing Identifies Novel Genes for Fetal Hemoglobin Response to Hydroxyurea in Children with Sickle Cell Anemia
Hydroxyurea has proven efficacy in children and adults with sickle cell anemia (SCA), but with considerable inter-individual… Expand
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2014
2014
A Case of Recurrent Anaplastic Meningioma of the Skull Base with Radiologic Response to Hydroxyurea
Anaplastic meningiomas are rare and aggressive tumors with a high propensity for local recurrence. Surgical resection and… Expand
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2012
2012
Genetic Predictors of Hemoglobin F Response to Hydroxyurea in Sickle Cell Anemia
Abstract 241 Although they ostensibly have a monogenetic disease, individuals with sickle cell anemia exhibit wide variability in… Expand
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2012
2012
SB202190 affects cell response to hydroxyurea-induced genotoxic stress in root meristems of Vicia faba.
Genotoxic stress caused by a variety of chemical and physical agents may lead to DNA breaks and genome instability. Response to… Expand
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2008
2008
Fetal Hemoglobin in Sickle Cell Anemia: A Genome-Wide Association Study of the Response to Hydroxyurea
Fetal hemoglobin (HbF) is the major genetic modulator of sickle cell anemia. Candidate gene-based and genome-wide association… Expand
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2004
2004
Genetic Polymorphisms Associated with Fetal Hemoglobin Response to Hydroxyurea in Patients with Sickle Cell Anemia.
Hydroxyurea (HU) is an effective treatment for most patients with symptomatic sickle cell anemia, yet the fetal hemoglobin (HbF… Expand
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Highly Cited
1997
Highly Cited
1997
Fetal hemoglobin in sickle cell anemia: determinants of response to hydroxyurea. Multicenter Study of Hydroxyurea.
Hydroxyurea (HU) can increase fetal hemoglobin (HbF) in sickle cell anemia (HbSS). To identify determinants of the HbF response… Expand
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