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response to hydroxyurea

Known as: response to HU 
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene… 
National Institutes of Health

Papers overview

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2019
2019
Robust clinical and laboratory response to hydroxyurea using pharmacokinetically guided dosing for young children with sickle cell anemia
Hydroxyurea is FDA‐approved and now increasingly used for children with sickle cell anemia (SCA), but dosing strategies… 
2019
2019
Pharmacoproteomics Profiling of Plasma From β‐Thalassemia Patients in Response to Hydroxyurea Treatment
β‐Thalassemia is a genetic disorder caused by defects in the β‐globin gene resulting in the absence or reduced synthesis of adult… 
2017
2017
Relationship Between Some Single-nucleotide Polymorphism and Response to Hydroxyurea Therapy in Iranian Patients With &bgr;-Thalassemia Intermedia
Objective: To evaluate the possible relationship between hydroxyurea (HU) response and some single-nucleotide polymorphism (SNP… 
2016
2016
Serum Paraoxonase Activity and Malondialdehyde Serum Concentrations Remain Unaffected in Response to Hydroxyurea Therapy in β‐Thalassemia Patients
β‐Thalassemia is the most common hereditary disorder characterized by reduced production of β‐globin chains of hemoglobin A (HbA… 
2015
2015
Treatment Response to Hydroxyurea in Beta Thalassemia
Introduction: Thalassemias are a group of haematological disorders due to quantitative defect of globin chain. Patients require… 
2014
2014
Whole Exome Sequencing Identifies Novel Genes for Fetal Hemoglobin Response to Hydroxyurea in Children with Sickle Cell Anemia
Hydroxyurea has proven efficacy in children and adults with sickle cell anemia (SCA), but with considerable inter-individual… 
2014
2014
A Case of Recurrent Anaplastic Meningioma of the Skull Base with Radiologic Response to Hydroxyurea
Anaplastic meningiomas are rare and aggressive tumors with a high propensity for local recurrence. Surgical resection and… 
2012
2012
Genetic Predictors of Hemoglobin F Response to Hydroxyurea in Sickle Cell Anemia
Abstract 241 Although they ostensibly have a monogenetic disease, individuals with sickle cell anemia exhibit wide variability in… 
2004
2004
Genetic Polymorphisms Associated with Fetal Hemoglobin Response to Hydroxyurea in Patients with Sickle Cell Anemia.
Hydroxyurea (HU) is an effective treatment for most patients with symptomatic sickle cell anemia, yet the fetal hemoglobin (HbF… 
Highly Cited
1997
Highly Cited
1997
Fetal hemoglobin in sickle cell anemia: determinants of response to hydroxyurea. Multicenter Study of Hydroxyurea.
Hydroxyurea (HU) can increase fetal hemoglobin (HbF) in sickle cell anemia (HbSS). To identify determinants of the HbF response… 
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