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response to hydroxyurea
Known as:
response to HU
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene…
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National Institutes of Health
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Papers overview
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2019
2019
Robust clinical and laboratory response to hydroxyurea using pharmacokinetically guided dosing for young children with sickle cell anemia
Patrick T. McGann
,
O. Niss
,
+9 authors
A. Vinks
American journal of hematology/oncology
2019
Corpus ID: 159040810
Hydroxyurea is FDA‐approved and now increasingly used for children with sickle cell anemia (SCA), but dosing strategies…
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2019
2019
Pharmacoproteomics Profiling of Plasma From β‐Thalassemia Patients in Response to Hydroxyurea Treatment
M. Zohaib
,
S. Ansari
,
T. Shamsi
,
R. Zubarev
,
S. Zarina
Journal of clinical pharmacology
2019
Corpus ID: 52097889
β‐Thalassemia is a genetic disorder caused by defects in the β‐globin gene resulting in the absence or reduced synthesis of adult…
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2017
2017
Relationship Between Some Single-nucleotide Polymorphism and Response to Hydroxyurea Therapy in Iranian Patients With &bgr;-Thalassemia Intermedia
M. Karimi
,
T. Zarei
,
+7 authors
H. Miri
Journal of pediatric hematology/oncology
2017
Corpus ID: 10991623
Objective: To evaluate the possible relationship between hydroxyurea (HU) response and some single-nucleotide polymorphism (SNP…
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2016
2016
Serum Paraoxonase Activity and Malondialdehyde Serum Concentrations Remain Unaffected in Response to Hydroxyurea Therapy in β‐Thalassemia Patients
M. Zohaib
,
S. Ansari
,
Zehra Hashim
,
T. Shamsi
,
S. Zarina
Journal of clinical pharmacology
2016
Corpus ID: 8828002
β‐Thalassemia is the most common hereditary disorder characterized by reduced production of β‐globin chains of hemoglobin A (HbA…
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2015
2015
Treatment Response to Hydroxyurea in Beta Thalassemia
Naghmi Asif
,
T. Anwar
,
+4 authors
K. Hassan
2015
Corpus ID: 38666404
Introduction: Thalassemias are a group of haematological disorders due to quantitative defect of globin chain. Patients require…
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2014
2014
Whole Exome Sequencing Identifies Novel Genes for Fetal Hemoglobin Response to Hydroxyurea in Children with Sickle Cell Anemia
V. Sheehan
,
Jacy R. Crosby
,
+10 authors
Jonathan M. Flanagan
PLoS ONE
2014
Corpus ID: 6193788
Hydroxyurea has proven efficacy in children and adults with sickle cell anemia (SCA), but with considerable inter-individual…
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2014
2014
A Case of Recurrent Anaplastic Meningioma of the Skull Base with Radiologic Response to Hydroxyurea
Joshua Gurberg
,
N. Bouganim
,
G. Shenouda
,
A. Zeitouni
Journal of Neurological Surgery Reports
2014
Corpus ID: 7958461
Anaplastic meningiomas are rare and aggressive tumors with a high propensity for local recurrence. Surgical resection and…
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2012
2012
Genetic Predictors of Hemoglobin F Response to Hydroxyurea in Sickle Cell Anemia
V. Sheehan
,
T. Howard
,
+8 authors
Jonathan M. Flanagan
2012
Corpus ID: 78644893
Abstract 241 Although they ostensibly have a monogenetic disease, individuals with sickle cell anemia exhibit wide variability in…
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2004
2004
Genetic Polymorphisms Associated with Fetal Hemoglobin Response to Hydroxyurea in Patients with Sickle Cell Anemia.
D. Wyszynski
,
C. Baldwin
,
+5 authors
M. Steinberg
2004
Corpus ID: 90486076
Hydroxyurea (HU) is an effective treatment for most patients with symptomatic sickle cell anemia, yet the fetal hemoglobin (HbF…
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Highly Cited
1997
Highly Cited
1997
Fetal hemoglobin in sickle cell anemia: determinants of response to hydroxyurea. Multicenter Study of Hydroxyurea.
M. Steinberg
,
Z. H. Lu
,
F. Barton
,
M. Terrin
,
S. Charache
,
G. Dover
Blood
1997
Corpus ID: 268431
Hydroxyurea (HU) can increase fetal hemoglobin (HbF) in sickle cell anemia (HbSS). To identify determinants of the HbF response…
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