FAQ

response to hydroxyurea

Known as: response to HU 
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1981-2017
0246819812017

Papers overview

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2009
2009
Response to hydroxyurea in beta thalassemia major and intermedia: experience in western India.
BACKGROUND The clinical and hematological response to hydroxyurea was evaluated in beta thalassemia patients in western India… (More)
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Highly Cited
2007
Highly Cited
2007
Switching from repression to activation: microRNAs can up-regulate translation.
AU-rich elements (AREs) and microRNA target sites are conserved sequences in messenger RNA (mRNA) 3' untranslated regions (3'UTRs… (More)
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2007
2007
Fetal hemoglobin in sickle cell anemia: genetic determinants of response to hydroxyurea
The increase in fetal hemoglobin (HbF) in response to hydroxyurea (HU) varies among patients with sickle cell anemia. Twenty-nine… (More)
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Highly Cited
2006
Highly Cited
2006
Rapid activation of ATR by ionizing radiation requires ATM and Mre11.
The ataxia-telangiectasia-mutated (ATM) and ATM- and Rad3-related (ATR) protein kinases are crucial regulatory proteins in… (More)
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2005
2005
Hydroxyurea in thalassemia intermedia—a promising therapy
Pharmacological agents such as hydroxyurea (HU) have been known to cause induction of fetal hemoglobin and possibly may alleviate… (More)
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2005
2005
Role of the iron mobilization and oxidative stress regulons in the genomic response of yeast to hydroxyurea
Hydroxyurea (HU) is a specific inhibitor of ribonucleotide reductase and thus impairs dNTP synthesis and DNA replication. The… (More)
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2004
2004
Response to hydroxyurea treatment in Iranian transfusion-dependent beta-thalassemia patients.
BACKGROUND AND OBJECTIVES Hydroxyurea (HU) is known to increase gamma-globin chain expression in postnatal life. The efficacy of… (More)
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Highly Cited
2001
Highly Cited
2001
The DNA replication checkpoint response stabilizes stalled replication forks.
In response to DNA damage and blocks to replication, eukaryotes activate the checkpoint pathways that prevent genomic instability… (More)
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2001
2001
Tof1p regulates DNA damage responses during S phase in Saccharomyces cerevisiae.
A tof1 mutant was recovered in a screen aimed at identifying genes involved specifically in the S phase branch of the MEC1… (More)
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Highly Cited
1999
Highly Cited
1999
A human Cds1-related kinase that functions downstream of ATM protein in the cellular response to DNA damage.
Checkpoints maintain the order and fidelity of the eukaryotic cell cycle, and defects in checkpoints contribute to genetic… (More)
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